Human Collagen Type XVII (COL17) ELISA Kit | COL17 elisa kit
Human Collagen Type XVII (COL17) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008]
Uniprot Description
May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane.
Research Articles on COL17
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Product Notes
The Human COL17 col17a1 (Catalog #AAA452824) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA452824 ELISA Kit recognizes Human COL17. It is sometimes possible for the material contained within the vial of "Collagen Type XVII (COL17), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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