Human Claudin 3 (CLDN3) ELISA Kit | CLDN3 elisa kit

Human Claudin 3 (CLDN3) ELISA Kit

Cat. Num. AAA451933

• Gene Names: CLDN3; RVP1; HRVP1; C7orf1; CPE-R2; CPETR2
• Reactivity: Human
• Synonyms: Claudin 3 (CLDN3); Human Claudin 3 (CLDN3) ELISA Kit; Calcium-activated neutral proteinase small subunit; Calcium-dependent protease small subunit; Calcium-dependent protease small subunit 1; Calpain regulatory subunit; CANP small subunit; CLDN3 elisa kit

• Reactivity: Human
• Sequence Length: 220

• Samples: Serum, plasma, tissue homogenates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.312-20ng/mL
• Sensitivity: 0.125ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Standard Curve/Testing Data

NCBI and Uniprot Product Information

• NCBI GI #: 4502875
• NCBI GeneID: 1365
• NCBI Accession #: NP_001297.1
• NCBI GenBank Nucleotide #: NM_001306.3
• UniProt Accession #: O15551
• Molecular Weight: 23,319 Da
• NCBI Official Full Name: claudin-3
• NCBI Official Synonym Full Names: claudin 3
• NCBI Official Symbol: CLDN3
• NCBI Official Synonym Symbols: RVP1; HRVP1; C7orf1; CPE-R2; CPETR2
• NCBI Protein Information: claudin-3
• UniProt Protein Name: Claudin-3
• Protein Family: Claudin
• UniProt Gene Name: CLDN3
• UniProt Synonym Gene Names: C7orf1; CPETR2; CPE-R 2; CPE-receptor 2; hRVP1

NCBI Description

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]

Uniprot Description

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.