Human Calcium/calmodulin dependent protein kinase type 1D (CAMK1D) ELISA Kit | CAMK1D elisa kit
Human Calcium/calmodulin dependent protein kinase type 1D (CAMK1D) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the Ca2+/calmodulin-dependent protein kinase 1 subfamily of serine/threonine kinases. The encoded protein may be involved in the regulation of granulocyte function through the chemokine signal transduction pathway. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
CAMK1D: a calcium/calmodulin-dependent S/T protein kinase of the CAMK group. Binding of calmodulin is thought to result in a conformational change and can lead to subsequent activation through phosphorylation by CAMKK1 and CAMKK2. Can be activated by CAMKK1 in a calcium-independent manner. Its Ca(2+)/CaM-dependent activity is enhanced 30-fold in vitro by phosphorylation at Thr180 by CaMKK1. Broadly expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes. May regulate calcium-mediated granulocyte function. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta and probably CREB1. Expression increases upon treatment of EC cells with DMSO and retinoic acid. Two isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; Kinase, protein; EC 2.7.11.17; CAMK group; CAMK1 family
Chromosomal Location of Human Ortholog: 10p13
Cellular Component: cytoplasm; nucleus
Molecular Function: calmodulin binding; calmodulin-dependent protein kinase activity; ATP binding
Biological Process: positive regulation of apoptosis; positive regulation of phagocytosis; regulation of dendrite development; activation of CREB transcription factor; inflammatory response; protein amino acid phosphorylation; negative regulation of apoptosis
Research Articles on CAMK1D
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Product Notes
The Human CAMK1D camk1d (Catalog #AAA7225369) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7225369 ELISA Kit recognizes Human CAMK1D. It is sometimes possible for the material contained within the vial of "Calcium/calmodulin dependent protein kinase type 1D (CAMK1D), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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