Typical Testing Data/Standard Curve (for reference only)

Human C-Myb ELISA Kit | C-Myb elisa kit

Human C-Myb ELISA Kit

Gene Names

MYB; efg; Cmyb; c-myb; c-myb_CDS

Reactivity

Human

Synonyms

C-Myb; Human C-Myb ELISA Kit; C-Myb elisa kit

Ordering
Cat. Num. AAA3803841 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Human

Sequence Length

637

Sensitivity

10 pg/mL

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for C-Myb elisa kit

Intended Uses: This C-MYB ELISA kit is intended Laboratory for Research use only. The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration of C-MYB in the sample, this C-MYB ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versus C-MYB concentration. The concentration of C-MYB in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

NCBI GI #

194328727

NCBI GeneID

4602

NCBI Accession #

NP_001123644

NCBI GenBank Nucleotide #

NP_001123644.1

UniProt Accession #

P10242

NCBI Official Full Name

transcriptional activator Myb isoform 3

NCBI Official Synonym Full Names

MYB proto-oncogene, transcription factor

NCBI Official Symbol

MYB

NCBI Official Synonym Symbols

efg; Cmyb; c-myb; c-myb_CDS

NCBI Protein Information

transcriptional activator Myb

UniProt Protein Name

Transcriptional activator Myb

UniProt Gene Name

MYB

UniProt Entry Name

MYB_HUMAN

NCBI Description

This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Uniprot Description

Myb: Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; Oncoprotein; DNA-binding

Chromosomal Location of Human Ortholog: 6q22-q23

Cellular Component: nuclear matrix; cytosol

Molecular Function: protein binding; chromatin binding

Biological Process: positive regulation of histone H3-K9 methylation; thymus development; transcription, DNA-dependent; in utero embryonic development; positive regulation of transcription, DNA-dependent; homeostasis of number of cells; positive regulation of histone H3-K4 methylation; negative regulation of transcription from RNA polymerase II promoter; chromatin remodeling; positive regulation of T-helper cell differentiation; regulation of transcription, DNA-dependent; calcium ion transport; B cell differentiation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; blood coagulation; embryonic gut development; G1/S transition of mitotic cell cycle

Research Articles on C-Myb

1. MiR-363-3p was significantly highly expressed in osteoporotic samples. Mechanistically, miR-363-3p promotes osteoclastogenesis and inhibits osteogenic differentiation by targeting PTEN and therefore activating PI3K/AKT signaling pathway. MiR-363-3p was activated by its upstream transcription activator MYB

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Product Notes

The Human C-Myb myb (Catalog #AAA3803841) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA3803841 ELISA Kit recognizes Human C-Myb. It is sometimes possible for the material contained within the vial of "C-Myb, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Human C-Myb ELISA Kit | C-Myb elisa kit