Human C-C Motif Chemokine 26 (CCL26) ELISA Kit | CCL26 elisa kit

Human C-C Motif Chemokine 26 (CCL26) ELISA Kit

Cat. Num. AAA9716159

• Gene Names: CCL26; IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha
• Reactivity: Human
• Synonyms: C-C Motif Chemokine 26 (CCL26); Human C-C Motif Chemokine 26 (CCL26) ELISA Kit; CCL26; IMAC; MGC126714; MIP-4a; MIP-4alpha; SCYA26; TSC-1; CC chemokine IMAC; chemokine N1; eotaxin-3; macrophage inflammatory protein 4-alpha; small inducible cytokine A26; small inducible cytokine subfamily A; CCL26 elisa kit

• Reactivity: Human
• Specificity: Human C-C motif chemokine 26 (CCL26) ELISA Kit has high sensitivity and excellent specificity for detection of Human CCL26. No significant cross-reactivity or interference between Human CCL26 and analogues was observed.
• Sequence Length: 94

• Assay Type: Sandwich ELISA (Quantitative)
• Samples: Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
• Detection Method: Colorimetric
• Usage Notes: * Do not mix components from different kit lots or use reagents beyond the kit expiration date.; * Allow all reagents to warm to room temperature for at least 30 minutes before opening.; * Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.; * Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.; * Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.; * It is recommended that all samples and standards be assayed in duplicate or triplicate.
• Preparation and Storage: Store at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

(Fig.1. Human C-C motif chemokine 26 (CCL26) Standard Curve.)

Related Product Information for CCL26 elisa kit

Description: This Human C-C motif chemokine 26 (CCL26) ELISA Kit employs a two-site sandwich ELISA to quantitate CCL26 in samples. An antibody specific for CCL26 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CCL26 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CCL26 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CCL26 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Background: Chemokine (C-C motif) ligand 26 (CCL26) is a small cytokine belonging to the CC chemokine family that is also called Eotaxin-3, Macrophage inflammatory protein 4-alpha (MIP-4-alpha), Thymic stroma chemokine-1 (TSC-2), and IMAC. It is expressed by several?????

NCBI and Uniprot Product Information

• NCBI GI #: 5174671
• NCBI GeneID: 10344
• NCBI Accession #: NP_006063.1
• NCBI GenBank Nucleotide #: NP_006063.1
• UniProt Accession #: Q9Y258
• NCBI Official Full Name: C-C motif chemokine 26
• NCBI Official Synonym Full Names: C-C motif chemokine ligand 26
• NCBI Official Symbol: CCL26
• NCBI Official Synonym Symbols: IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha
• NCBI Protein Information: C-C motif chemokine 26
• UniProt Protein Name: C-C motif chemokine 26
• Protein Family: C-C motif chemokine
• UniProt Gene Name: CCL26
• UniProt Synonym Gene Names: SCYA26; MIP-4-alpha; TSC-1
• UniProt Entry Name: CCL26_HUMAN

NCBI Description

This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008]

Uniprot Description

CCL26: Chemotactic for eosinophils and basophils. Binds to CCR3. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Chemokine; Secreted

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: extracellular space

Molecular Function: chemokine activity

Biological Process: cell-cell signaling; positive regulation of actin filament polymerization; immune response; positive regulation of endothelial cell proliferation; chemotaxis; inflammatory response; signal transduction; positive regulation of cell migration