Human B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain, CD79A ELISA Kit | CD79A elisa kit
Human B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain, CD79A ELISA Kit
Principle of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with human BFGF-4 antibody. BFGF-4 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated human BFGF-4 Antibody is added and binds to BFGF-4 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated BFGF-4 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of human BFGF-4. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
NCBI and Uniprot Product Information
NCBI Description
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
Ig-alpha: an integral membrane protein that associates with surface immunoglobulin B lymphocyte antigen receptor multimeric complex. Surface Ig non-covalently associates with 2 other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. Two alternatively spliced isoforms have been described.
Protein type: Membrane protein, integral; Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: multivesicular body; integral to membrane; plasma membrane; B cell receptor complex; lipid raft; external side of plasma membrane
Molecular Function: transmembrane receptor activity
Biological Process: B cell proliferation; B cell receptor signaling pathway; B cell activation; B cell differentiation
Disease: Agammaglobulinemia 3, Autosomal Recessive
Research Articles on CD79A
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Product Notes
The Human CD79A cd79a (Catalog #AAA1603954) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA1603954 ELISA Kit recognizes Human CD79A. It is sometimes possible for the material contained within the vial of "B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain, CD79A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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