Human Autophagy related protein 16 1 (ATG16L1) ELISA Kit | ATG16L1 elisa kit
Human Autophagy related protein 16 1 (ATG16L1) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]
Uniprot Description
ATG16: Plays an essential role in autophagy. Homooligomer. Interacts with ATG5. Part of either the minor and major complexes respectively composed of 4 sets of ATG12-ATG5 and ATG16L1 (400 kDa) or 8 sets of ATG12-ATG5 and ATG16L1 (800 kDa). Belongs to the WD repeat ATG16 family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Autophagy; Membrane protein, peripheral; Adaptor/scaffold
Chromosomal Location of Human Ortholog: 2q37.1
Cellular Component: pre-autophagosomal structure membrane; autophagic vacuole; axoneme
Molecular Function: identical protein binding; protein binding
Biological Process: protein transport; protein homooligomerization; autophagic vacuole formation
Disease: Inflammatory Bowel Disease 10
Research Articles on ATG16L1
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Product Notes
The Human ATG16L1 atg16l1 (Catalog #AAA7201610) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7201610 ELISA Kit recognizes Human ATG16L1. It is sometimes possible for the material contained within the vial of "Autophagy related protein 16 1 (ATG16L1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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