Human ATG10 autophagy related 10 homolog (S. cerevisiae) ELISA Kit | ATG10 elisa kit

Human Ubiquitin-like-conjugating enzyme ATG10, ATG10 ELISA Kit

Cat. Num. AAA9318935

• Gene Names: ATG10; APG10; APG10L; pp12616
• Reactivity: Human
• Synonyms: ATG10 autophagy related 10 homolog (S. cerevisiae); Human Ubiquitin-like-conjugating enzyme ATG10; ATG10 ELISA Kit; Human Ubiquitin-like-conjugating enzyme ATG10 (ATG10) ELISA kit; APG10; APG10L; DKFZp586I0418; FLJ13954; pp12616; APG10 autophagy 10-like; ATG10 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Canine Serum, Plasma Or Tissue Homogenates Samples
• Assay Type: Quantitative Sandwich
• Detection Range: 62.5pg/ml-2000pg/ml
• Sensitivity: 10pg/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for ATG10 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of ATF4 (hereafter termed "analyte") in undiluted original Canine serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 196162717
• NCBI GeneID: 83734
• NCBI Accession #: NP_001124500.1
• NCBI GenBank Nucleotide #: NM_001131028.1
• UniProt Accession #: Q9H0Y0; Q6PIX1; Q9H842; B2RE09
• Molecular Weight: 25,279 Da
• NCBI Official Full Name: ubiquitin-like-conjugating enzyme ATG10
• NCBI Official Synonym Full Names: autophagy related 10
• NCBI Official Symbol: ATG10
• NCBI Official Synonym Symbols: APG10; APG10L; pp12616
• NCBI Protein Information: ubiquitin-like-conjugating enzyme ATG10; autophagy-related protein 10; ATG10 autophagy related 10 homolog
• UniProt Protein Name: Ubiquitin-like-conjugating enzyme ATG10
• Protein Family: Ubiquitin-like-conjugating enzyme
• UniProt Gene Name: ATG10
• UniProt Synonym Gene Names: APG10L; PP12616; APG10-like
• UniProt Entry Name: ATG10_HUMAN

NCBI Description

Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]

Uniprot Description

ATG10: E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3. Belongs to the ATG10 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 6.3.2.-; Ubiquitin conjugating system; Autophagy

Chromosomal Location of Human Ortholog: 5q14.1

Cellular Component: cytoplasm; intracellular

Molecular Function: APG12 conjugating enzyme activity; ligase activity

Biological Process: protein transport; protein modification by small protein conjugation; positive regulation of protein modification process; protein amino acid lipidation; autophagy