Typical Testing Data/Standard Curve (for reference only)
Human alpha-Synuclein, alpha-SYN ELISA Kit | alpha-SYN elisa kit
Human alpha-Synuclein, alpha-SYN ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
SNCA: a member of the synuclein family. Abundantly expressed in the brain. Inhibits phospholipase D2 selectively. May integrate presynaptic signaling and membrane trafficking. Implicated in the pathogenesis of Parkinson's disease. A major component of amyloid plaques in the brains of patients with Alzheimer's disease. Two alternatively spliced isoforms transcripts have been identified.
Protein type: Adaptor/scaffold
Cellular Component: Golgi apparatus; nuclear outer membrane; mitochondrion; terminal button; inclusion body; cytosol; platelet alpha granule membrane; synaptic vesicle; perinuclear region of cytoplasm; cytoplasm; synapse; cytoplasmic vesicle membrane; rough endoplasmic reticulum; intracellular membrane-bound organelle; cell; fibril; cell cortex; actin cytoskeleton; growth cone; cytoskeleton; axon; plasma membrane; ribosome; nerve terminal; nucleus
Molecular Function: identical protein binding; protein domain specific binding; histone binding; zinc ion binding; kinesin binding; ferrous iron binding; microtubule binding; metal ion binding; caspase inhibitor activity; beta-tubulin binding; magnesium ion binding; phosphoprotein binding; protein N-terminus binding; Hsp70 protein binding; oxidoreductase activity; calcium ion binding; arachidonic acid binding; dynein binding; protein binding; enzyme binding; phospholipase binding; copper ion binding; phospholipid binding; tau protein binding; alpha-tubulin binding
Biological Process: regulation of long-term neuronal synaptic plasticity; negative regulation of serotonin uptake; synaptic transmission, dopaminergic; regulation of acyl-CoA biosynthetic process; adult locomotory behavior; mitochondrial membrane organization and biogenesis; negative regulation of norepinephrine uptake; regulation of neurotransmitter secretion; microglial cell activation; positive regulation of endocytosis; response to lipopolysaccharide; negative regulation of monooxygenase activity; dopamine biosynthetic process; negative regulation of caspase activity; fatty acid metabolic process; regulation of dopamine secretion; dopamine metabolic process; positive regulation of neurotransmitter secretion; positive regulation of synaptic transmission; negative regulation of dopamine uptake; negative regulation of histone acetylation; synaptic transmission; response to magnesium ion; negative regulation of exocytosis; negative regulation of protein amino acid phosphorylation; behavioral response to cocaine; receptor internalization; phospholipid metabolic process; regulation of neuron apoptosis; synapse organization and biogenesis; negative regulation of neuron apoptosis; response to iron(II) ion; positive regulation of receptor recycling; caspase activation; response to drug; neutral lipid metabolic process; protein destabilization; negative regulation of microtubule polymerization; regulation of glutamate secretion; regulation of macrophage activation; synaptic vesicle transport; positive regulation of peptidyl-serine phosphorylation; negative regulation of dopamine metabolic process; organelle ATP synthesis coupled electron transport; regulation of locomotion; synaptic vesicle endocytosis; positive regulation of release of sequestered calcium ion into cytosol; regulation of excitatory postsynaptic membrane potential; negative regulation of transporter activity; regulation of neuronal synaptic plasticity; negative regulation of apoptosis
Research Articles on alpha-SYN
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Product Notes
The Human alpha-SYN snca (Catalog #AAA2602614) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2602614 ELISA Kit recognizes Human alpha-SYN. It is sometimes possible for the material contained within the vial of "alpha-Synuclein, alpha-SYN, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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