Human Aggrecan (AGC) ELISA Kit | AGC elisa kit

Human Aggrecan (AGC) ELISA Kit

Cat. Num. AAA455259

• Gene Names: ACAN; AGC1; SEDK; AGCAN; CSPG1; MSK16; CSPGCP
• Reactivity: Human
• Synonyms: Aggrecan (AGC); Human Aggrecan (AGC) ELISA Kit; ACAN AGC1 AGCAN CSPG1 CSPCP CSPGCP MSK16 SEDK Cartilage-specific proteoglycan core protein Large Aggregating Proteoglycan Chondroitin Sulfate Proteoglycan 1; AGC elisa kit

• Reactivity: Human
• Sequence Length: 2415

• Samples: Serum, plasma and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.468-30ng/mL
• Sensitivity: 0.16ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 129886
• NCBI GeneID: 176
• UniProt Accession #: P16112; Q13650; Q9UCD3; Q9UCP4; Q9UCP5; Q9UDE0
• Molecular Weight: 239,235 Da
• NCBI Official Full Name: Aggrecan core protein
• NCBI Official Synonym Full Names: aggrecan
• NCBI Official Symbol: ACAN
• NCBI Official Synonym Symbols: AGC1; SEDK; AGCAN; CSPG1; MSK16; CSPGCP
• NCBI Protein Information: aggrecan core protein
• UniProt Protein Name: Aggrecan core protein
• UniProt Gene Name: ACAN
• UniProt Synonym Gene Names: AGC1; CSPG1; MSK16; CSPCP; Chondroitin sulfate proteoglycan 1

NCBI Description

This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.