Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Adenylate cyclase type 9 (ADCY9) Standard Curve.)
Human Adenylate Cyclase Type 9 (ADCY9) ELISA Kit | ADCY9 elisa kit
Human Adenylate Cyclase Type 9 (ADCY9) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Adenylate cyclase type 9 (ADCY9) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Adenylate cyclase type 9 (ADCY9) Standard Curve.)
Background: Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin.Like mouse Adcy9, the predicted human ADCY9 protein contains 12 transmembrane domains, Asn-linked glycosylation sites, and cAMP-dependent protein kinase phosphorylation sites; however, these proteins differ in the C2b domain due to a frameshift in the human ADCY9 coding sequence relative to the coding sequence of mouse Adcy9. Northern blot analysis detected 8.5- and 6.3-kb ADCY9 transcripts in all human tissues examined.
NCBI and Uniprot Product Information
NCBI Description
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008]
Uniprot Description
ADCY9: May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Protein type: Transporter; Adenylyl cyclase; Lyase; Membrane protein, integral; Membrane protein, multi-pass; Transporter, aquaporin family; EC 4.6.1.1; Nucleotide Metabolism - purine
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: metal ion binding; ATP binding; adenylate cyclase activity
Biological Process: epidermal growth factor receptor signaling pathway; synaptic transmission; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; phospholipase C activation; water transport; activation of protein kinase A; energy reserve metabolic process; renal water homeostasis; innate immune response; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; signal transduction; transmembrane transport; G-protein signaling, adenylate cyclase activating pathway
Research Articles on ADCY9
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Product Notes
The Human ADCY9 adcy9 (Catalog #AAA9714597) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9714597 ELISA Kit recognizes Human ADCY9. It is sometimes possible for the material contained within the vial of "Adenylate Cyclase Type 9 (ADCY9), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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