Human Adenylate cyclase type 7 (ADCY7) ELISA Kit | ADCY7 elisa kit

Human Adenylate cyclase type 7 (ADCY7) ELISA Kit

Cat. Num. AAA269978

• Gene Names: ADCY7; AC7
• Reactivity: Human
• Synonyms: Adenylate cyclase type 7 (ADCY7); Human Adenylate cyclase type 7 (ADCY7) ELISA Kit; ADCY7 elisa kit

• Reactivity: Human
• Specificity: No cross-reaction with other factors.
• Sequence Length: 1080

• Samples: Human serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant ADCY7 concentration
• Assay Type: Sandwich
• Detection Range: 50 ng/ml-0.78 ng/ml
• Sensitivity: 0.1 ng/ml.
• Intra-assay Precision: <= 8%
• Inter-assay Precision: <= 12%
• Preparation and Storage: Store all reagents at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for ADCY7 elisa kit

Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human ADCY7 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

NCBI and Uniprot Product Information

• NCBI GI #: 4557255
• NCBI GeneID: 113
• NCBI Accession #: NP_001105.1
• NCBI GenBank Nucleotide #: NM_001114.4
• Molecular Weight: 120,308 Da
• NCBI Official Full Name: adenylate cyclase type 7 isoform 1
• NCBI Official Synonym Full Names: adenylate cyclase 7
• NCBI Official Symbol: ADCY7
• NCBI Official Synonym Symbols: AC7
• NCBI Protein Information: adenylate cyclase type 7; adenylyl cyclase 7; ATP pyrophosphate-lyase 7; adenylate cyclase type VII
• UniProt Protein Name: Adenylate cyclase type 7
• Protein Family: Adenylate cyclase
• UniProt Gene Name: ADCY7
• UniProt Synonym Gene Names: KIAA0037
• UniProt Entry Name: ADCY7_HUMAN

NCBI Description

This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences. Several transcript variants have been observed for this gene, but the full-length natures of only two have been determined so far. [provided by RefSeq, Oct 2013]

Uniprot Description

ADCY7: This is a membrane-bound, calcium-inhibitable adenylyl cyclase. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Protein type: Transporter; Nucleotide Metabolism - purine; EC 4.6.1.1; Membrane protein, multi-pass; Adenylyl cyclase; Lyase; Transporter, aquaporin family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16q12.1

Cellular Component: plasma membrane; integral to membrane

Molecular Function: metal ion binding; ATP binding; adenylate cyclase activity

Biological Process: epidermal growth factor receptor signaling pathway; maternal process involved in pregnancy; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; water transport; activation of protein kinase A; signal transduction; G-protein signaling, adenylate cyclase activating pathway; synaptic transmission; phospholipase C activation; positive regulation of cAMP biosynthetic process; energy reserve metabolic process; innate immune response; renal water homeostasis; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; transmembrane transport