Human A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) ELISA Kit | ADAMTS1 elisa kit

Human A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) ELISA Kit

Cat. Num. AAA455561

• Gene Names: ADAMTS1; C3-C5; METH1
• Reactivity: Human
• Synonyms: A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1); Human A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) ELISA Kit; C3-C5; METH1; ADAMTS1 elisa kit

• Reactivity: Human
• Sequence Length: 967

• Samples: Tissue homogenates, cell lysates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.781-50ng/mL
• Sensitivity: 0.27ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 50845384
• NCBI GeneID: 9510
• NCBI Accession #: NP_008919.3
• NCBI GenBank Nucleotide #: NM_006988.4
• UniProt Accession #: Q9UHI8; Q9NSJ8; Q9P2K0; Q9UH83; Q9UP80; D3DSD5
• Molecular Weight: 105,358 Da
• NCBI Official Full Name: A disintegrin and metalloproteinase with thrombospondin motifs 1 preproprotein
• NCBI Official Synonym Full Names: ADAM metallopeptidase with thrombospondin type 1 motif 1
• NCBI Official Symbol: ADAMTS1
• NCBI Official Synonym Symbols: C3-C5; METH1
• NCBI Protein Information: A disintegrin and metalloproteinase with thrombospondin motifs 1
• UniProt Protein Name: A disintegrin and metalloproteinase with thrombospondin motifs 1
• Protein Family: A disintegrin and metalloproteinase with thrombospondin motifs
• UniProt Gene Name: ADAMTS1
• UniProt Synonym Gene Names: KIAA1346; METH1; ADAM-TS 1; ADAM-TS1; ADAMTS-1

NCBI Description

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function. [provided by RefSeq, Jul 2008]

Uniprot Description

Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover (). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.