ZW10 blocking peptide
ZW10 Peptide - C-terminal region
Target Description: This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. [provided by RefSeq, Aug 2011]
Uniprot Description
ZW10: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum. Belongs to the ZW10 family.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 11q23.2
Cellular Component: kinetochore microtubule; kinetochore; spindle pole; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; cytoplasm; cytosol; nucleus
Molecular Function: centromeric DNA binding; protein binding
Biological Process: meiosis; ER to Golgi vesicle-mediated transport; protein transport; mitotic sister chromatid segregation; establishment of mitotic spindle orientation; cell division; mitotic cell cycle checkpoint; regulation of exit from mitosis; protein complex assembly; mitotic cell cycle; mitotic metaphase plate congression; Golgi organization and biogenesis
Research Articles on ZW10
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Product Notes
The ZW10 zw10 (Catalog #AAA3246475) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The ZW10 Peptide - C-terminal region reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: Synthetic peptide located within the following region: NKKYQEEVPV YVPKWMPFKE LMMMLQASLQ EIGDRWADGK GPLAAAFSSS. It is sometimes possible for the material contained within the vial of "ZW10, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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