TRIM6 blocking peptide

TRIM6 Immunizing Peptide

Cat. Num. AAA427389

• Gene Names: TRIM6; RNF89
• Reactivity: Human
• Synonyms: TRIM6; TRIM6 Immunizing Peptide; tripartite motif containing 6; RNF89; OTTHUMP00000069818; OTTHUMP00000069819; OTTHUMP00000069820; OTTHUMP00000197092; OTTHUMP00000220648; OTTHUMP00000220649; OTTHUMP00000220650; RING finger protein 89; tripartite motif-containing 6; tripartite moti; TRIM6 (aa118-131); TRIM6 blocking peptide

• Reactivity: Human
• Form/Format: 100ug of dried peptide
• Sequence: KQLKAVLCADHGEK
• Sequence Length: 516

• Preparation and Storage: Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 51477692
• NCBI GeneID: 117854
• NCBI Accession #: NP_001003818.1; NP_477514.1
• NCBI GenBank Nucleotide #: NM_001003818.2
• Molecular Weight: 36,400 Da
• NCBI Official Full Name: tripartite motif-containing protein 6 isoform 1
• NCBI Official Synonym Full Names: tripartite motif containing 6
• NCBI Official Symbol: TRIM6
• NCBI Official Synonym Symbols: RNF89
• NCBI Protein Information: tripartite motif-containing protein 6
• UniProt Protein Name: Tripartite motif-containing protein 6
• Protein Family: Tripartite motif-containing protein
• UniProt Gene Name: TRIM6
• UniProt Synonym Gene Names: RNF89
• UniProt Entry Name: TRIM6_HUMAN

NCBI Description

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from this gene into the downstream TRIM34 gene has also been observed, which results in a fusion product from these neighboring family members. [provided by RefSeq, Oct 2010]

Uniprot Description

TRIM6: is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from this gene into the downstream TRIM34 gene has also been observed, which results in a fusion product from these neighboring family members. [provided by RefSeq, Oct 2010]

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 11p15.4

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function: ligase activity; protein binding; protein binding, bridging; protein kinase binding; transcription factor binding; zinc ion binding

Biological Process: negative regulation of transcription, DNA-dependent; negative regulation of viral genome replication; positive regulation of cytokine secretion during immune response; positive regulation of defense response to virus by host; positive regulation of peptidyl-serine phosphorylation; protein polyubiquitination; response to lipopolysaccharide