SERPINA12 blocking peptide

SERPINA12 Immunizing Peptide

Cat. Num. AAA425979

• Gene Names: SERPINA12; OL-64
• Reactivity: Human
• Synonyms: SERPINA12; SERPINA12 Immunizing Peptide; serpin peptidase inhibitor; clade A (alpha-1 antiproteinase; antitrypsin); member 12; OL-64; serine (or cysteine) proteinase inhibitor; vaspin; visceral adipose-specific SERPIN; SERPINA12 blocking peptide

• Reactivity: Human
• Form/Format: 100ug of dried peptide
• Sequence: C-RARWKHEFDPNVTK
• Sequence Length: 414

• Preparation and Storage: Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 27777657
• NCBI GeneID: 145264
• NCBI Accession #: NP_776249.1
• NCBI GenBank Nucleotide #: NM_173850.3
• Molecular Weight: 47,175 Da
• NCBI Official Full Name: serpin A12
• NCBI Official Synonym Full Names: serpin family A member 12
• NCBI Official Symbol: SERPINA12
• NCBI Official Synonym Symbols: OL-64
• NCBI Protein Information: serpin A12
• UniProt Protein Name: Serpin A12
• Protein Family: Serpin
• UniProt Gene Name: SERPINA12
• UniProt Synonym Gene Names: Vaspin
• UniProt Entry Name: SPA12_HUMAN

Uniprot Description

SERPINA12: May modulate insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues. Belongs to the serpin family.

Protein type: Secreted; Secreted, signal peptide; Inhibitor

Chromosomal Location of Human Ortholog: 14q32.13

Cellular Component: extracellular space; plasma membrane

Molecular Function: serine-type endopeptidase inhibitor activity

Biological Process: glucose metabolic process; negative regulation of gluconeogenesis; negative regulation of lipid biosynthetic process; positive regulation of insulin receptor signaling pathway; positive regulation of phosphoinositide 3-kinase cascade