Testing Data
(TTR antibody at 1/2000 dilution interacts with recombinant TTR protein with a DsbA tag. Predicted band size: 40KDa. Observed band size: 40KDa.)
anti-Human TTR Antibody | anti-TTR antibody
TTR Antibody
WB: 1:100-1:2000
Testing Data
(TTR antibody at 1/2000 dilution interacts with recombinant TTR protein with a DsbA tag. Predicted band size: 40KDa. Observed band size: 40KDa.)
Testing Data
(TTR antibody at 1/2000 dilution interacts with recombinant TTR protein with a DsbA tag. Predicted band size: 40KDa. Observed band size: 40KDa.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. [provided by RefSeq, Aug 2017]
Uniprot Description
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
Research Articles on TTR
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Product Notes
The TTR ttr (Catalog #AAA850465) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The TTR Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TTR can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:5000-1:20000 WB: 1:100-1:2000. Researchers should empirically determine the suitability of the TTR ttr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TTR, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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