anti-Human TAF5L Antibody | anti-TAF5L antibody

TAF5L Antibody

Cat. Num. AAA8513784

• Gene Names: TAF5L; PAF65B
• Reactivity: Human
• Applications: Western Blot
• Purity: Immunogen affinity purified
• Synonyms: TAF5L; TAF5L Antibody; TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L; PCAF-associated factor 65 beta; PAF65-beta; PAF65B; anti-TAF5L antibody

• Reactivity: Human
• Specificity: TAF5L Antibody detects endogenous levels of total TAF5L
• Purity/Purification: Immunogen affinity purified
• Form/Format: In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 325

• Applicable Applications for anti-TAF5L antibody: WB: 1:500-1:1000
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthesized peptide
• Preparation and Storage: Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis of extracts from HT-29 cells and COS-7 cells, using TAF5L antibody.)

NCBI and Uniprot Product Information

• NCBI GI #: 69122931
• NCBI GeneID: 27097
• NCBI Accession #: NP_001020418.1
• NCBI GenBank Nucleotide #: NM_001025247.1
• UniProt Accession #: O75529; Q5TDI5; Q5TDI6; Q8IW31
• Molecular Weight: 66 KD
• NCBI Official Full Name: TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L isoform b
• NCBI Official Synonym Full Names: TATA-box binding protein associated factor 5 like
• NCBI Official Symbol: TAF5L
• NCBI Official Synonym Symbols: PAF65B
• NCBI Protein Information: TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L
• UniProt Protein Name: TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L
• Protein Family: TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor
• UniProt Gene Name: TAF5L
• UniProt Synonym Gene Names: PAF65B; PAF65-beta

NCBI Description

The product of this gene belongs to the WD-repeat TAF5 family of proteins. This gene encodes a protein that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. The encoded protein is structurally similar to one of the histone-like TAFs, TAF5. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex.