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anti-Human SYCP3 Antibody | anti-SYCP3 antibody

SYCP3 Antibody

Gene Names
SYCP3; COR1; SCP3; SPGF4; RPRGL4
Reactivity
Human
Applications
ELISA
Purity
Protein G-Sepharose affinity purified.
Synonyms
SYCP3; SYCP3 Antibody; Mouse monoclona IgG l to SYCP3; anti-SYCP3 antibody
Ordering
For Research Use Only!
Reactivity
Human
Purity/Purification
Protein G-Sepharose affinity purified.
Form/Format
Liquid
Sequence Length
236
Applicable Applications for anti-SYCP3 antibody
ELSIA (EIA)
Application Notes
ELISA: 1:5000-1:20000
Immunogen
Recombinant full length of Human SYCP3.
Preservative
0.02% Sodium Azide, 50% glycerol, 1% BSA, PBS, pH7.4.
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-SYCP3 antibody
During meiosis, the homologous chromosomes pair and recombine, a process essential for generating genetically distinct haploid cells. The unique behavior displayed by meiotic chromosomes has been linked to the activities of a meiosis-specific supramolecular proteinaceous structure, the synaptonemal complex (SC). Three meiosis-specific components of the SC have been characterized in mammals, SCP1, SCP2 and SCP3. SCP3 has a C-terminal coiled-coil domain that has been shown to promote homotypic interactions in vitro.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,729 Da
NCBI Official Full Name
synaptonemal complex protein 3
NCBI Official Synonym Full Names
synaptonemal complex protein 3
NCBI Official Symbol
SYCP3
NCBI Official Synonym Symbols
COR1; SCP3; SPGF4; RPRGL4
NCBI Protein Information
synaptonemal complex protein 3
UniProt Protein Name
Synaptonemal complex protein 3
UniProt Gene Name
SYCP3
UniProt Synonym Gene Names
SCP3; SCP-3

NCBI Description

This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010]

Uniprot Description

Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells (). Required for normal meiosis during spermatogenesis and male fertility (PubMed:14643120). Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2 ().

Research Articles on SYCP3

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Product Notes

The SYCP3 sycp3 (Catalog #AAA850451) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The SYCP3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SYCP3 can be used in a range of immunoassay formats including, but not limited to, ELSIA (EIA). ELISA: 1:5000-1:20000. Researchers should empirically determine the suitability of the SYCP3 sycp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYCP3, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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