Western Blot (WB)
(Western blot analysis SRD5A2 using HepG2 whole cell lysates)
anti-Human SRD5A2 Antibody | anti-SRD5A2 antibody
SRD5A2 Antibody
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using Sulfo linkTM Coupling Resin (Thermo Fisher Scientific).
Synonyms
SRD5A2; SRD5A2 Antibody; 3 oxo 5 alpha steroid 4 dehydrogenase 2; 3 –oxo-5- alpha-steroid;4-dehydrogenase 2; 5 alpha SR2; 5 alpha-SR2; 5ART2; e II 5 alpha reductase; EC; MGC138457 ; Micropenis; included; S5A2_HUMAN; S5AR 2; SR type 2; Steroid 5 alpha reductase 2; Steroid 5- alpha-reductase 2; Steroid-5- alpha-reductase; alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4- dehydrogenase alpha 2); Type II 5 alpha reductase; anti-SRD5A2 antibody
Reactivity
Human
Specificity
SRD5A2 Antibody detects endogenous levels of total SRD5A2.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using Sulfo linkTM Coupling Resin (Thermo Fisher Scientific).
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4 150 mM NaCI, 0.02% sodium azide and 50% glycerol.
Sequence Length
254
Applicable Applications for anti-SRD5A2 antibody
Western Blot (WB), ELISA (peptide)
Application Notes
Western Blot (WB) 1:1000-3000
ELISA (peptide) 1:20000-1:40000
ELISA (peptide) 1:20000-1:40000
Immunogen
A synthesized peptide derived from human SRD5A2.
Preparation and Storage
Store at -20°C/ 1 year.
Western Blot (WB)
(Western blot analysis SRD5A2 using HepG2 whole cell lysates)
Western Blot (WB)
(Western blot analysis SRD5A2 using HepG2 whole cell lysates)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28 kDa
NCBI Official Full Name
3-oxo-5-alpha-steroid 4-dehydrogenase 2
NCBI Official Synonym Full Names
steroid 5 alpha-reductase 2
NCBI Official Symbol
SRD5A2
NCBI Protein Information
3-oxo-5-alpha-steroid 4-dehydrogenase 2
UniProt Protein Name
3-oxo-5-alpha-steroid 4-dehydrogenase 2
Protein Family
UniProt Gene Name
SRD5A2
UniProt Synonym Gene Names
S5AR 2
NCBI Description
This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008]
Uniprot Description
Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Research Articles on SRD5A2
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Product Notes
The SRD5A2 srd5a2 (Catalog #AAA8517575) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The SRD5A2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SRD5A2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (peptide). Western Blot (WB) 1:1000-3000 ELISA (peptide) 1:20000-1:40000. Researchers should empirically determine the suitability of the SRD5A2 srd5a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SRD5A2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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