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Testing Data

anti-Human PEVR1 Antibody | anti-PEVR1 antibody

PEVR1 Antibody

Gene Names
SLC52A2; PAR1; RFT3; RFVT2; hRFT3; BVVLS2; GPCR41; GPR172A; D15Ertd747e
Reactivity
Human
Applications
Western Blot, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
PEVR1; PEVR1 Antibody; G protein-coupled receptor 172A; G-protein coupled receptor GPCR41; GPCR; GPCR41; GPR172A; PAR1; PERV-A receptor 1; PEVR2; porcine endogenous retrovirus A receptor 1; anti-PEVR1 antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
PEVR1 antibody detects endogenous levels of total PEVR1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
445
Applicable Applications for anti-PEVR1 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:10000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human PEVR1.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

Testing Data

Western Blot (WB)

(Peptide-+ Western blot analysis of extracts from A549 cells, using PEVR1 antibody. Immunofluorescence analysis of MCF-7 cells, using PEVR1 antibody.)

Western Blot (WB) (Peptide-+ Western blot analysis of extracts from A549 cells, using PEVR1 antibody. Immunofluorescence analysis of MCF-7 cells, using PEVR1 antibody.)
References
Ericsson T.A.; Proc. Natl. Acad. Sci. U.S.A. 100:6759-6764(2003). Ota T.; Nat. Genet. 36:40-45(2004). The MGC Project Team; Genome Res. 14:2121-2127(2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,777 Da
NCBI Official Full Name
solute carrier family 52, riboflavin transporter, member 2 isoform 1
NCBI Official Synonym Full Names
solute carrier family 52 member 2
NCBI Official Symbol
SLC52A2
NCBI Official Synonym Symbols
PAR1; RFT3; RFVT2; hRFT3; BVVLS2; GPCR41; GPR172A; D15Ertd747e
NCBI Protein Information
solute carrier family 52, riboflavin transporter, member 2
UniProt Protein Name
Solute carrier family 52, riboflavin transporter, member 2
UniProt Gene Name
SLC52A2
UniProt Synonym Gene Names
GPR172A; PAR1; RFT3; PERV-A receptor 1; hRFT3

NCBI Description

This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia. [provided by RefSeq, Jul 2012]

Uniprot Description

Riboflavin transporter. Riboflavin transport is Na+-independent but moderately pH-sensitive. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin. Weakly inhibited by flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN). In case of infection by retroviruses, acts as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A).

Research Articles on PEVR1

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Product Notes

The PEVR1 slc52a2 (Catalog #AAA856004) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The PEVR1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PEVR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:10000. Researchers should empirically determine the suitability of the PEVR1 slc52a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PEVR1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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