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Western Blot (WB) (Western blot analysis of extracts from 293 cells, using NRXN3 antibody.)

anti-Human NRXN3 Antibody | anti-NRXN3 antibody

NRXN3 Antibody

Gene Names
NRXN3; C14orf60
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
NRXN3; NRXN3 Antibody; Na(+)/H(+) exchange regulatory cofactor NHE-RF2; NHERF-2; NHE3 kinase A regulatory protein E3KARP; SRY-interacting protein 1; SIP-1; Sodium-hydrogen exchanger regulatory factor 2; Solute carrier family 9 isoform A3 regulatory factor 2; Tyrosine kinase activator; anti-NRXN3 antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
NRXN3 antibody detects endogenous levels of total NRXN3 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
459
Applicable Applications for anti-NRXN3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human NRXN3.
Preparation and Storage
Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts from 293 cells, using NRXN3 antibody.)

Western Blot (WB) (Western blot analysis of extracts from 293 cells, using NRXN3 antibody.)
References
Poulat F., J. Biol. Chem. 272:7167-7172(1997) [PubMed: 9054412]. Reczek D., J. Cell Biol. 139:169-179(1997) [PubMed: 9314537]. Yun C.H.C., Proc. Natl. Acad. Sci. U.S.A. 94:3010-3015(1997) [PubMed: 9096337]. Reczek D., J. Cell Biol. 139:169-179(1997) [PubMed: 9314537]. Yun C.H.C., Proc. Natl. Acad. Sci. U.S.A. 94:3010-3015(1997) [PubMed: 9096337].

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
180,599 Da
NCBI Official Full Name
neurexin 3 isoform 3
NCBI Official Synonym Full Names
neurexin 3
NCBI Official Symbol
NRXN3
NCBI Official Synonym Symbols
C14orf60
NCBI Protein Information
neurexin 3
UniProt Protein Name
Neurexin-3-beta
Protein Family
UniProt Gene Name
NRXN3
UniProt Synonym Gene Names
KIAA0743; NRXN3-CTF

NCBI Description

This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder. [provided by RefSeq, Dec 2012]

Uniprot Description

Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May play a role in angiogenesis ().

Research Articles on NRXN3

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Product Notes

The NRXN3 nrxn3 (Catalog #AAA852781) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The NRXN3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NRXN3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:20000. Researchers should empirically determine the suitability of the NRXN3 nrxn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NRXN3, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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