anti-Human NBPF4 Antibody | anti-NBPF4 antibody

NBPF4 Antibody

Cat. Num. AAA8509888

• Reactivity: Human
• Applications: Immunohistochemistry, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: NBPF4; NBPF4 Antibody; Neuroblastoma breakpoint family member 4; anti-NBPF4 antibody

• Reactivity: Human
• Specificity: NBPF4 antibody detects endogenous levels of total NBPF4 protein.
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 638

• Applicable Applications for anti-NBPF4 antibody: Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: IHC: 1:50-1:100; ELISA: 1:40000
• Immunogen: The antiserum was produced against synthesized peptide derived from internal of human NBPF4.
• Preparation and Storage: Store at-20 degree C for 1 year.

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human testis tissue using NBPF4 antibody.)

References

Ota T., Nat. Genet. 36:40-45(2004). Vandepoele K., Mol. Biol. Evol. 22:2265-2274(2005).

NCBI and Uniprot Product Information

• NCBI GI #: 221218991
• NCBI GeneID: 148545
• NCBI Accession #: NP_001137461.1
• NCBI GenBank Nucleotide #: NM_001143989.2
• UniProt Accession #: Q96M43; Q5T483
• Molecular Weight: 72,053 Da
• NCBI Official Full Name: neuroblastoma breakpoint family member 4
• NCBI Official Synonym Full Names: NBPF member 4
• NCBI Official Symbol: NBPF4
• NCBI Protein Information: neuroblastoma breakpoint family member 4
• UniProt Protein Name: Neuroblastoma breakpoint family member 4
• Protein Family: Neuroblastoma breakpoint family
• UniProt Gene Name: NBPF4

NCBI Description

This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Mar 2013]

Uniprot Description

MiscellaneousEncoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.