anti-Human MOV10L1 Antibody | anti-MOV10L1 antibody

MOV10L1 Antibody

Cat. Num. AAA8515065

• Gene Names: MOV10L1; CHAMP; DJ402G11.8
• Reactivity: Human
• Applications: Western Blot
• Purity: Immunogen affinity purified
• Synonyms: MOV10L1; MOV10L1 Antibody; EC 3.6.1.-; helicase Mov10l1; M10L1; Moloney leukemia virus 10-like 1; MOV10-like 1; anti-MOV10L1 antibody

• Reactivity: Human
• Specificity: MOV10L1 Antibody detects endogenous levels of total MOV10L1
• Purity/Purification: Immunogen affinity purified
• Form/Format: In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 1165

• Applicable Applications for anti-MOV10L1 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: A synthesized peptide
• Preparation and Storage: Store at-20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of extracts from RAW264.7 cells and HeLa cells, using MOV10L1 antibody.)

NCBI and Uniprot Product Information

• NCBI GI #: 255759906
• NCBI GeneID: 54456
• NCBI Accession #: NP_001157576.1
• NCBI GenBank Nucleotide #: NM_001164104.1
• UniProt Accession #: Q9BXT6; Q5TGD5; Q8NBD4; Q9NXW3; Q9UFB3; Q9UGX9; A7E211; A8MXC6; B7WPP1; B7Z7R1; F5H403
• Molecular Weight: 140 KD
• NCBI Official Full Name: RNA helicase Mov10l1 isoform 2
• NCBI Official Synonym Full Names: Mov10 RISC complex RNA helicase like 1
• NCBI Official Symbol: MOV10L1
• NCBI Official Synonym Symbols: CHAMP; DJ402G11.8
• NCBI Protein Information: RNA helicase Mov10l1
• UniProt Protein Name: RNA helicase Mov10l1
• Protein Family: RNA helicase
• UniProt Gene Name: MOV10L1
• UniProt Synonym Gene Names: MOV10-like protein 1

NCBI Description

This gene is similar to a mouse gene that encodes a putative RNA helicase and shows testis-specific expression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]

Uniprot Description

ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5'-3' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins.