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Western Blot (WB) (Western blot analysis of extracts from HuvEc cells, using MIA2 antibody. For Research Use Only)

anti-Human MIA2 Antibody | anti-MIA2 antibody

MIA2 Antibody

Gene Names
MIA2; MEA6; MGEA; TALI; MGEA6; CTAGE5; MGEA11
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
MIA2; MIA2 Antibody; Melanoma inhibitory activity protein 2; anti-MIA2 antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
MIA2 antibody detects endogenous levels of total MIA2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
1412
Applicable Applications for anti-MIA2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human MIA2.
Preparation and Storage
Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts from HuvEc cells, using MIA2 antibody. For Research Use Only)

Western Blot (WB) (Western blot analysis of extracts from HuvEc cells, using MIA2 antibody. For Research Use Only)
References
Bosserhoff A.K., J. Biol. Chem. 278:15225-15231(2003). Heilig R., Nature 421:601-607(2003). Mural R.J., Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
74,089 Da
NCBI Official Full Name
cTAGE family member 5 isoform 8
NCBI Official Synonym Full Names
melanoma inhibitory activity 2
NCBI Official Symbol
MIA2
NCBI Official Synonym Symbols
MEA6; MGEA; TALI; MGEA6; CTAGE5; MGEA11
NCBI Protein Information
cTAGE family member 5; melanoma inhibitory activity protein 2
UniProt Protein Name
Melanoma inhibitory activity protein 2
UniProt Gene Name
MIA2

NCBI Description

This gene encodes s receptor in the endoplasmic reticulum, which plays a role in the export of large pre-chylomicrons and pre-very low density lipoproteins (pre-VLDLs). Three major classes of transcripts are generated from this gene- melanoma inhibitory activity 2-specific transcripts, cTAGE family member 5-specific transcripts and transcripts that include exons from both these transcript species (TANGO1-like or TALI). Additionally, alternative splicing in these transcripts results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Sep 2016]

Uniprot Description

Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Isoform 1 plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum (PubMed:27138255). Thereby, may play a role in cholesterol and triglyceride homeostasis ().

Research Articles on MIA2

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Product Notes

The MIA2 mia2 (Catalog #AAA856081) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The MIA2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MIA2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:20000. Researchers should empirically determine the suitability of the MIA2 mia2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MIA2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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