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Testing Data

anti-Human FEV Antibody | anti-FEV antibody

FEV Antibody

Gene Names
FEV; PET-1; HSRNAFEV
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
FEV; FEV Antibody; FEV (ETS oncogene family); FEV (fifth Ewing variant); Fifth Ewing variant protein; HSRNAFEV; PC12 ETS domain-containing transcription factor 1; PC12 ETS factor 1; Pet-1; PET1; Protein FEV; anti-FEV antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
FEV antibody detects endogenous levels of total FEV protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
238
Applicable Applications for anti-FEV antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:3000
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized peptide derived from N-terminal of human FEV.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

Testing Data
References
Peter M., Oncogene 14:1159-1164(1997). Hillier L.W., Nature 434:724-731(2005). Maurer P., Oncogene 22:3319-3329(2003).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25,030 Da
NCBI Official Full Name
protein FEV
NCBI Official Synonym Full Names
FEV, ETS transcription factor
NCBI Official Symbol
FEV
NCBI Official Synonym Symbols
PET-1; HSRNAFEV
NCBI Protein Information
protein FEV
UniProt Protein Name
Protein FEV
Protein Family
UniProt Gene Name
FEV
UniProt Synonym Gene Names
PET1; PC12 ETS factor 1; Pet-1

NCBI Description

This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations. [provided by RefSeq, Jul 2008]

Uniprot Description

Functions as a transcriptional regulator. According to PubMed:12761502, it functions as a transcriptional repressor. Functions in the differentiation and the maintenance of the central serotonergic neurons. May play a role in cell growth.

Research Articles on FEV

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Product Notes

The FEV fev (Catalog #AAA858059) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The FEV Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FEV can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:3000 ELISA: 1:40000. Researchers should empirically determine the suitability of the FEV fev for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FEV, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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