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Western Blot (WB) (Western blot analysis of EFEMP2 expression in 3T3 cells)

anti-Human EFEMP2 Antibody | anti-EFEMP2 antibody

EFEMP2 Antibody

Gene Names
EFEMP2; MBP1; UPH1; FBLN4; ARCL1B
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Immunogen affinity purified
Synonyms
EFEMP2; EFEMP2 Antibody; EGF-containing fibulin-like extracellular matrix protein 2; FBLN4; anti-EFEMP2 antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
EFEMP2 Antibody detects endogenous levels of total EFEMP2
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
443
Applicable Applications for anti-EFEMP2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:100-1:500
Immunogen
A synthesized peptide derived from human EFEMP2
Preparation and Storage
Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis of EFEMP2 expression in 3T3 cells)

Western Blot (WB) (Western blot analysis of EFEMP2 expression in 3T3 cells)
Related Product Information for anti-EFEMP2 antibody
Defects in EFEMP2 are a cause of cutis laxa autosomal recessive type 1 (ARCL1) [MIM:219100]. Hereditary cutis laxa refers to a heterogeneous group of connective tissue disorders characterized by cutaneous abnormalities and variable systemic manifestations. The most constant clinical feature is loose skin, sagging over the face and trunk.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
49 kDa
NCBI Official Full Name
EGF-containing fibulin-like extracellular matrix protein 2
NCBI Official Synonym Full Names
EGF containing fibulin extracellular matrix protein 2
NCBI Official Symbol
EFEMP2
NCBI Official Synonym Symbols
MBP1; UPH1; FBLN4; ARCL1B
NCBI Protein Information
EGF-containing fibulin-like extracellular matrix protein 2
UniProt Protein Name
EGF-containing fibulin-like extracellular matrix protein 2
UniProt Gene Name
EFEMP2
UniProt Synonym Gene Names
FBLN4; FIBL-4

NCBI Description

A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein encoded by this gene contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011]

Research Articles on EFEMP2

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Product Notes

The EFEMP2 efemp2 (Catalog #AAA8511840) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The EFEMP2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EFEMP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:100-1:500. Researchers should empirically determine the suitability of the EFEMP2 efemp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EFEMP2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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