anti-Human AIBZIP/CREB3L4 Antibody | anti-CREB3L4 antibody

Goat anti-AIBZIP/CREB3L4, Biotinylated Antibody

Cat. Num. AAA423694

• Gene Names: CREB3L4; JAL; hJAL; ATCE1; CREB3; CREB4; AIBZIP
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Synonyms: AIBZIP/CREB3L4; Goat anti-AIBZIP/CREB3L4; Biotinylated Antibody; Goat Anti-AIBZIP/CREB3L4 Antibody; CREB3L4; cAMP responsive element binding protein 3-like 4; AIBZIP; ATCE1; CREB3; CREB4; JAL; hJAL; CREB-4; androgen-induced basic leucine zipper protein; attaching to CRE-like 1; cAMP responsive element binding protein 1; cAMP-responsive element-binding protein 3-like protein 4; cAMP-responsive element-binding protein 4; cyclic AMP-responsive element-binding protein 4; tisp40; transcript induced in spermiogenesis protein 40; anti-CREB3L4 antibody

• Reactivity: Human
• Purity/Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Form/Format: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Sequence Length: 395

• Applicable Applications for anti-CREB3L4 antibody: Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Pep-ELISA: antibody detection limit dilution 1:32000.; WB: Approx 50kDa band observed in Human Placenta lysates. Recommended concentration: 1-3ug/ml.
• Immunogen Sequence: Peptide with sequence CPSGRIRSVLHADEM., from the C Terminus of the protein sequence according to NP_570968.1; NP_001242909.1.
• Peptide Sequence + C: CPSGRIRSVLHADEM.
• Epitope: C Terminus
• Note: This antibody is expected to recognize both reported isoforms (NP_570968.1; NP_001242909.1). Reported variants represent identical protein: NP_001242908.1, NP_570968.1, NP_001242907.1 Reported variants represent identical protein: NP_001242909.1, NP_001242910.1
• Preparation and Storage: Aliquot and store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Biotinylated (1ug/ml) staining of Human Placenta lysate (35ug protein in RIPA buffer), exactly mirroring its parental non-biotinylated product. Primary incubation was 1 hour. Detected by chemiluminescence, using streptavidin-HRP and using NAP blocker as a substitute for skimmed milk.)

NCBI and Uniprot Product Information

• NCBI GI #: 18702325
• NCBI GeneID: 148327
• NCBI Accession #: NP_570968.1; NP_001242909.1
• NCBI GenBank Nucleotide #: NM_130898.3
• UniProt Accession #: Q8TEY5; Q5T4L0; Q86YW6; D3DV62
• Molecular Weight: 43.4kDa
• NCBI Official Full Name: cyclic AMP-responsive element-binding protein 3-like protein 4 isoform 1
• NCBI Official Synonym Full Names: cAMP responsive element binding protein 3 like 4
• NCBI Official Symbol: CREB3L4
• NCBI Official Synonym Symbols: JAL; hJAL; ATCE1; CREB3; CREB4; AIBZIP
• NCBI Protein Information: cyclic AMP-responsive element-binding protein 3-like protein 4
• UniProt Protein Name: Cyclic AMP-responsive element-binding protein 3-like protein 4
• Protein Family: Cyclic AMP-responsive element-binding protein 3-like protein
• UniProt Gene Name: CREB3L4
• UniProt Synonym Gene Names: AIBZIP; CREB4; JAL; cAMP-responsive element-binding protein 3-like protein 4; AIbZIP; ATCE1; CREB-4; cAMP-responsive element-binding protein 4; Tisp40

NCBI Description

This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Uniprot Description

Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements ().