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Typical Testing Data/Standard Curve (for reference only)

Human Tankyrase 2 (TNKS2) Antibody Pair Kit | TNKS2 antibody pair kit

Human Tankyrase 2 (TNKS2) Antibody Pair Kit (with Standard)

Gene Names
TNKS2; TNKL; ARTD6; TANK2; pART6; PARP5B; PARP5C; PARP-5b; PARP-5c
Reactivity
Human
Applications
ELISA, ELISA
Synonyms
Tankyrase 2 (TNKS2); Human Tankyrase 2 (TNKS2) Antibody Pair Kit (with Standard); PARP5B; PARP5C; TANK2; TNKL; Tankyrase-like protein; ADP-ribosyltransferase diphtheria toxin-like 6; TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2; TNKS2 antibody pair kit
Ordering
For Research Use Only!
Reactivity
Human
Applicable Applications for TNKS2 antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
Samples
Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates and Other Biological Fluids
Detection Range
0.312-20ng/mL
Standard
Recombinant TNKS2 (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Product Categories/Family for TNKS2 antibody pair kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
126,918 Da
NCBI Official Full Name
tankyrase-2
NCBI Official Synonym Full Names
tankyrase 2
NCBI Official Symbol
TNKS2
NCBI Official Synonym Symbols
TNKL; ARTD6; TANK2; pART6; PARP5B; PARP5C; PARP-5b; PARP-5c
NCBI Protein Information
tankyrase-2
UniProt Protein Name
Tankyrase-2
Protein Family
UniProt Gene Name
TNKS2
UniProt Synonym Gene Names
PARP5B; TANK2; TNKL; TANK2; ARTD6

Uniprot Description

Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Stimulates 26S proteasome activity.

Research Articles on TNKS2

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Product Notes

The Human TNKS2 tnks2 (Catalog #AAA2102207) is an Antibody Pair Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2102207 Antibody Pair Kit recognizes Human TNKS2. AAA Biotech's Tankyrase 2 (TNKS2) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex. Researchers should empirically determine the suitability of the TNKS2 tnks2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tankyrase 2 (TNKS2), Antibody Pair Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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