Human Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) Antibody Pair Kit | PDK1 antibody pair kit
Human Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) Antibody Pair Kit (with Standard)
Reactivity
Human
Applications
ELISA, ELISA
Synonyms
Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1); Human Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) Antibody Pair Kit (with Standard); [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1; mitochondrial; PDK1 antibody pair kit
Reactivity
Human
Applicable Applications for PDK1 antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
Samples
Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates and Other Biological Fluids
Detection Range
31.2-2000ng/mL
Standard
Recombinant PDK1 (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
Product Categories/Family for PDK1 antibody pair kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
49,081 Da
NCBI Official Full Name
pyruvate dehydrogenase kinase, isozyme 1
NCBI Official Synonym Full Names
pyruvate dehydrogenase kinase 1
NCBI Official Symbol
Pdk1
NCBI Protein Information
pyruvate dehydrogenase kinase, isozyme 1
UniProt Protein Name
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
Protein Family
UniProt Gene Name
Pdk1
UniProt Synonym Gene Names
Pdh; PDH kinase 1
NCBI Description
catalyzes the phosphorylation and inactivation of the pyruvate dehydrogenase complex [RGD, Feb 2006]
Uniprot Description
Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress.
Research Articles on PDK1
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Product Notes
The Human PDK1 pdk1 (Catalog #AAA2101978) is an Antibody Pair Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2101978 Antibody Pair Kit recognizes Human PDK1. AAA Biotech's Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex. Researchers should empirically determine the suitability of the PDK1 pdk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1), Antibody Pair Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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