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Human Integrin Alpha 2B (ITGa2B) Antibody Pair Kit | ITGa2B antibody pair kit

Human Integrin Alpha 2B (ITGa2B) Antibody Pair Kit (with Standard)

Gene Names
ITGA2B; GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16; PPP1R93
Reactivity
Human
Applications
ELISA, ELISA
Synonyms
Integrin Alpha 2B (ITGa2B); Human Integrin Alpha 2B (ITGa2B) Antibody Pair Kit (with Standard); CD41; CD41B; ITG-A2B; GTA; GP2B; GPIIb; HPA3; Platelet Glycoprotein IIb Of IIb/IIIa Complex; Antigen CD41; ITGa2B antibody pair kit
Ordering
For Research Use Only!
Reactivity
Human
Applicable Applications for ITGa2B antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
Samples
Tissue Homogenates, Cell Lysates and Other Biological Fluids
Detection Range
0.312-20ng/mL
Standard
Recombinant ITGa2B (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
Product Categories/Family for ITGa2B antibody pair kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
103,218 Da
NCBI Official Full Name
integrin alpha-IIb preproprotein
NCBI Official Synonym Full Names
integrin subunit alpha 2b
NCBI Official Symbol
ITGA2B
NCBI Official Synonym Symbols
GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16; PPP1R93
NCBI Protein Information
integrin alpha-IIb
UniProt Protein Name
Integrin alpha-IIb
Protein Family
UniProt Gene Name
ITGA2B
UniProt Synonym Gene Names
GP2B; ITGAB; GPIIb

NCBI Description

This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016]

Uniprot Description

Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Research Articles on ITGa2B

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Product Notes

The Human ITGa2B itga2b (Catalog #AAA2099824) is an Antibody Pair Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2099824 Antibody Pair Kit recognizes Human ITGa2B. AAA Biotech's Integrin Alpha 2B (ITGa2B) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex. Researchers should empirically determine the suitability of the ITGa2B itga2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Integrin Alpha 2B (ITGa2B), Antibody Pair Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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