Human Heat Shock Protein 75kDa, Mitochondrial (HSP75) Antibody Pair Kit | HSP75 antibody pair kit

Human Heat Shock Protein 75kDa, Mitochondrial (HSP75) Antibody Pair Kit (with Standard)

Cat. Num. AAA2102553

• Gene Names: TRAP1; HSP75; HSP 75; HSP90L; TRAP-1
• Reactivity: Human
• Applications: ELISA, ELISA
• Synonyms: Heat Shock Protein 75kDa; Mitochondrial (HSP75); Human Heat Shock Protein 75kDa; Mitochondrial (HSP75) Antibody Pair Kit (with Standard); TRAP1; HSP90L; TNF Receptor-Associated Protein 1; Tumor necrosis factor type 1 receptor-associated protein; HSP75 antibody pair kit

• Reactivity: Human

• Applicable Applications for HSP75 antibody pair kit: ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
• Samples: Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates and Other Biological Fluids
• Detection Range: 31.2-2000ng/mL
• Standard: Recombinant HSP75 (Lyophilized, 1 vial-10ug)
• Capture Antibody: Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
• Detection Antibody: Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
• Producte Usage: Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
• Antibody Support Pack: Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685

Product Categories/Family for HSP75 antibody pair kit

Signal transduction

NCBI and Uniprot Product Information

• NCBI GI #: 440309857
• NCBI GeneID: 10131
• NCBI Accession #: NP_001258978.1
• NCBI GenBank Nucleotide #: NM_001272049.1
• UniProt Accession #: Q12931; O43642; O75235; Q9UHL5; B4DR68; D3DUC8; F5H897
• Molecular Weight: 74,267 Da
• NCBI Official Full Name: heat shock protein 75 kDa, mitochondrial isoform 2
• NCBI Official Synonym Full Names: TNF receptor associated protein 1
• NCBI Official Symbol: TRAP1
• NCBI Official Synonym Symbols: HSP75; HSP 75; HSP90L; TRAP-1
• NCBI Protein Information: heat shock protein 75 kDa, mitochondrial
• UniProt Protein Name: Heat shock protein 75 kDa, mitochondrial
• UniProt Gene Name: TRAP1
• UniProt Synonym Gene Names: HSP75; HSP 75; TRAP-1

NCBI Description

This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Uniprot Description

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.