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Human Defensin Alpha 3, Neutrophil Specific (DEFa3) Antibody Pair Kit | DEFa3 antibody pair kit

Human Defensin Alpha 3, Neutrophil Specific (DEFa3) Antibody Pair Kit (with Standard)

Gene Names
DEFA3; HP3; DEF3; HNP3; HP-3; HNP-3
Reactivity
Human
Applications
ELISA, ELISA
Synonyms
Defensin Alpha 3; Neutrophil Specific (DEFa3); Human Defensin Alpha 3; Neutrophil Specific (DEFa3) Antibody Pair Kit (with Standard); HNP3; DEF3; HNP-2; Neutrophil defensin 2; DEFa3 antibody pair kit
Ordering
For Research Use Only!
Reactivity
Human
Applicable Applications for DEFa3 antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
Samples
Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates and Other Biological Fluids
Detection Range
0.94-60ng/mL
Standard
Recombinant DEFa3 (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
Product Categories/Family for DEFa3 antibody pair kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
10,245 Da
NCBI Official Full Name
defensin, alpha 3, neutrophil-specific
NCBI Official Synonym Full Names
defensin alpha 3
NCBI Official Symbol
DEFA3
NCBI Official Synonym Symbols
HP3; DEF3; HNP3; HP-3; HNP-3
NCBI Protein Information
neutrophil defensin 3
UniProt Protein Name
Neutrophil defensin 3
Protein Family
UniProt Gene Name
DEFA3
UniProt Synonym Gene Names
DEF3; HP-3; HP3; HP-2; HP2

NCBI Description

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation. [provided by RefSeq, Oct 2014]

Uniprot Description

Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.

Research Articles on DEFa3

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Product Notes

The Human DEFa3 defa3 (Catalog #AAA2090329) is an Antibody Pair Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2090329 Antibody Pair Kit recognizes Human DEFa3. AAA Biotech's Defensin Alpha 3, Neutrophil Specific (DEFa3) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex. Researchers should empirically determine the suitability of the DEFa3 defa3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Defensin Alpha 3, Neutrophil Specific (DEFa3), Antibody Pair Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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