MIP2 active protein
MIP2 protein
Applications
User optimized
Purity
> 98% pure
Synonyms
MIP2; MIP2 protein; MIP 2; Growth Regulated protein; MGSA beta protein; MIP-2 protein; MIP 2 protein; GRO2 protein; Melanoma Growth Stimulatory Activity protein; Viral Macrophage inflammatory Protein-2 protein; MIP-2; CXCL2 protein; MIP2 active protein
Host
Human
Purity/Purification
> 98% pure
Form/Format
Supplied as a lyophilized powder.
Sequence
Region of MIP2 protein corresponding to amino acids LGASWHRPDK CCLGYQKRPL PQVLLSSWYP TSQLCSKPGV IFLTKRGRQV CADKSKDWVK KLMQQLPVTA.
Sequence Length
94
Applicable Applications for MIP2 active protein
User optimized
Protein Type
Recombinant
Biological Significance
vMIP-2 is a chemokine analog encoded by human herpes virus, and has been shown to have antagonist activity towards several chemokine receptors. Recombinant vMIP-2 is a 7.9 kDa protein consisting of 70 amino acids including the four highly conserved cysteine residues present in CC chemokines.
Bioactivity
Determined by the inhibitory effect on mon degree Cyte migration response to human MIP-1 alpha using a concentration range of 1.0ug-10.0ug/ml of viral MIP-2 will inhibit 25ng/ml of human MIP-1 alpha.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug(1 EU/ug).
Expression System
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for MIP2 active protein
Purified recombinant Human MIP2 protein
Product Categories/Family for MIP2 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
7.9 kDa
NCBI Official Full Name
Viral macrophage inflammatory protein 2
NCBI Official Symbol
K4
NCBI Protein Information
interleukin 8-like CC chemokine
UniProt Protein Name
Viral macrophage inflammatory protein 2
Protein Family
UniProt Gene Name
ORF K4
UniProt Synonym Gene Names
vMIP-II
UniProt Entry Name
VMI2_HHV8P
Uniprot Description
Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.
Research Articles on MIP2
Similar Products
Product Notes
The MIP2 orf k4 (Catalog #AAA539529) is an Active Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MIP2 can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the MIP2 orf k4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Region of MIP2 protein correspond ing to amino acids LGASWHRPDK CCLGYQKRPL PQVLLSSWYP TSQLCSKPGV IFLTKRGRQV CADKSKDWVK KLMQQLPVTA. It is sometimes possible for the material contained within the vial of "MIP2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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