HGF active protein
HGF protein
Applications
User optimized
Purity
> 98% pure
Synonyms
HGF; HGF protein; SF protein; Scatter Factor protein; Hepatopoietin protein; Hepatocyte Growth Factor protein; HPTA protein; HGF active protein
Host
Human
Purity/Purification
> 98% pure
Form/Format
Lyophilized from 0.1M L-Arginine HCL, with 10mM tris, pH8.0 and 200mM NaCl. Reconstitute in water to a concentration of 0.5 mg/ml.
Sequence Length
6
Applicable Applications for HGF active protein
User optimized
Protein Type
Recombinant
Biological Significance
HGF is a mesenchymally derived potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and Mouse HGF are cross-reactive. Human HGF is expressed as a linear 697 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains (a-chain and beta-chain) held by a single disulfide bond resulting in formation of a biologically active heterodimer.
Bioactivity
The ED50 was determined by the dose-dependent stimulation of the proliferation of monkey 4MBr-5 cells was found to be in the range of 20.0-40.0 ng/ml.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
Hi-5 cells
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for HGF active protein
Purified recombinant Human HGF protein
Product Categories/Family for HGF active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
hepatocyte growth factor, partial
Protein Family
Similar Products
Product Notes
The HGF (Catalog #AAA537869) is an Active Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's HGF can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the HGF for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HGF, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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