CTGF active protein
CTGF protein
Gene Names
CTGF; CCN2
Applications
User optimized
Purity
> 95% pure
Synonyms
CTGF; CTGF protein; CCN2 protein; HCS24 protein; Hypertrophic chondrocyte-specific protein 24 protein; Connective Tissue Growth Factor protein; CTGF active protein
Host
Human
Purity/Purification
> 95% pure
Form/Format
Lyophilized from 10 mM NaC2H3O2, pH 6.0. Reconstitute in water to a concentration of 0.1 - 1.0 mg/ml.
Concentration
5ug lyophilized (varies by lot)
Sequence
Region of CTGF protein corresponding to amino acids MGKKCIRTPK ISKPIKFELS GCTSMKTYRA KFCGVCTDGR CCTPHRTTTL PVEFKCPDGE VMKKNMMFIK TCACHYNCPG DNDIFESLYY RKMYGDMA.
Sequence Length
344
Applicable Applications for CTGF active protein
User optimized
Protein Type
Recombinant
Biological Significance
CTGF is a member of the CCN family of secreted cysteine rich regulatory proteins and is the major mitogenic and chemoattractant protein produced by umbilical vein and vascular endothelial cells. CTGF stimulates the proliferation and differentiation of chondrocytes, induces angiogenesis, promotes cell adhesion of fibroblasts, endothelial, and epithelial cells, and binds to IGF, TGF beta1, and BMP-4. Cell migration and adhesion are signaled through binding to specific cell surface integrins and to heparin sulfate proteoglycans CTGF (98 a.a.), a lower molecular weight isoform containing the C-terminal portion of the full length CTGF protein, exerts full heparin binding, cell adhesion, and mitogenic CTGF activity.
Bioactivity
Determined by the dose-dependent stimulation of the proliferation of HUVEC cells. The expected ED50 for this effect is 1.0-2.0 ug/ml.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for CTGF active protein
Purified recombinant Human CTGF protein
Product Categories/Family for CTGF active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
11.2 kDa
NCBI Official Full Name
connective tissue growth factor
NCBI Official Synonym Full Names
connective tissue growth factor
NCBI Official Symbol
CTGF
NCBI Official Synonym Symbols
CCN2
NCBI Protein Information
connective tissue growth factor
UniProt Protein Name
Connective tissue growth factor
Protein Family
UniProt Gene Name
CTGF
UniProt Entry Name
Q98TQ8_CHICK
Research Articles on CTGF
Similar Products
Product Notes
The CTGF ctgf (Catalog #AAA538277) is an Active Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CTGF can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the CTGF ctgf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Region of CTGF protein correspond ing to amino acids MGKKCIRTPK ISKPIKFELS GCTSMKTYRA KFCGVCTDGR CCTPHRTTTL PVEFKCPDGE VMKKNMMFIK TCACHYNCPG DNDIFESLYY RKMYGDMA. It is sometimes possible for the material contained within the vial of "CTGF, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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