Functional Assay (FA)
(Induction of alkaline phosphatase in C3H/10T1/2 cells by Human BMP2 protein.)
BMP2 active protein
BMP2 protein
Applications
Functional Assay
Purity
> 97% pureBMP2 protein was purified by affinity chromatography.
Synonyms
BMP2; BMP2 protein; BMP 2; BMP-2 protein; Bone Morphogenetic Protein 2 protein; BMP 2 protein; BMP-2; BMP2 active protein
Host
Human
Purity/Purification
> 97% pure
BMP2 protein was purified by affinity chromatography.
BMP2 protein was purified by affinity chromatography.
Form/Format
Supplied as a sterile liquid with 0.1 M glycine, 1%BSA
Sequence Length
104
Applicable Applications for BMP2 active protein
Functional Assay
Application Notes
The ED50 of this protein, as measured by CTLL-2 proliferation assay, is less than or equal to 175 pg/ml. This corresponds to a specific activity of greater than or equal to 5.7 x 10e6 Units/mg.
Protein Type
Recombinant
Biological Significance
BMP-2 is one of fifteen bone morphogenetic proteins belonging to the TGF-beta superfamily. The BMPs were first identified as the active factors in demineralized bone matrix, with transcripts later being discovered in many other types of tissue. They are synthesized as large precursor molecules that must be cleaved into their active form and dimerize in order to exhibit functional activity. These dimers may include two identical or distinct BMP chains. BMP responsiveness appears to be limited to multipotent and immature cells. The BMPs are essential for osteogenesis and organogenesis during embryonic development, and also play a role in fracture and wound healing in adults.
Bioactivity
The ED50 of this protein, asdetermined by alkaline phosphataseinduction in C3H/10T1/2 cells, is 0.25-1ug/ml. This corresponds to a specific activity of 4x103 - 1x10^3 Units/mg.
Endotoxin Levels
Less than 0.01 ng/ug cytokine as determined by the LAL assay.
Expression System
E Coli
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at -70 degree C or less.
Functional Assay (FA)
(Induction of alkaline phosphatase in C3H/10T1/2 cells by Human BMP2 protein.)
Functional Assay (FA)
(Induction of alkaline phosphatase in C3H/10T1/2 cells by Human BMP2 protein.)
Related Product Information for BMP2 active protein
Purified recombinant Human BMP2 protein
Product Categories/Family for BMP2 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
13 kDa
NCBI Official Full Name
BMP2, partial
NCBI Official Symbol
BMP2
NCBI Protein Information
bone morphogenetic protein 2
UniProt Protein Name
BMP2
Protein Family
UniProt Gene Name
BMP2
UniProt Entry Name
G8FNR8_SHEEP
Similar Products
Product Notes
The BMP2 bmp2 (Catalog #AAA5304499) is an Active Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's BMP2 can be used in a range of immunoassay formats including, but not limited to, Functional Assay. The ED50 of this protein, as measured by CTLL-2 proliferation assay, is less than or equal to 175 pg/ml. This corresponds to a specific activity of greater than or equal to 5.7 x 10e6 Units/mg. Researchers should empirically determine the suitability of the BMP2 bmp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BMP2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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