Human 5-hydroxytryptamine (serotonin) receptor 3A ELISA Kit | HTR3A elisa kit
Human 5-hydroxytryptamine receptor 3A, HTR3A ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
5-HT(3): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3A sub-subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Channel, ligand-gated; Transporter, ion channel; Membrane protein, integral; Channel, cation
Chromosomal Location of Human Ortholog: 11q23.1
Cellular Component: postsynaptic membrane; cell soma; axon; integral to plasma membrane; cytoplasm; plasma membrane; cell junction
Molecular Function: serotonin binding; voltage-gated potassium channel activity; serotonin-activated cation-selective channel activity; serotonin receptor activity; receptor activity
Biological Process: synaptic transmission; response to ethanol; transport; digestion; response to cocaine; transmembrane transport; serotonin receptor signaling pathway
Research Articles on HTR3A
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Product Notes
The Human HTR3A htr3a (Catalog #AAA9319154) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9319154 ELISA Kit recognizes Human HTR3A. It is sometimes possible for the material contained within the vial of "5-hydroxytryptamine (serotonin) receptor 3A, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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