5-hydroxytryptamine receptor 2A (HTR2A) Recombinant Protein | HTR2A recombinant protein
Recombinant Dog 5-hydroxytryptamine receptor 2A (HTR2A)
NCBI and Uniprot Product Information
Uniprot Description
Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production
By similarity.
Subunit structure: Interacts with MPDZ and INADL. May interact with MPP3, PRDX6, DLG4, DLG1, CASK, APBA1 and MAGI2
By similarity.
Subcellular location: Cell membrane; Multi-pass membrane protein
By similarity. Note: Localizes to the postsynaptic thickening of axo-dendritic synapses
By similarity.
Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
Research Articles on HTR2A
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Product Notes
The HTR2A htr2a (Catalog #AAA1253625) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-470. The amino acid sequence is listed below: MDVLFEDNAP LSPTTSSLMP SNGDPRLYGN DLNAGDANTS DAFNWTVDAE NRTNLSCEGC LSPPCFSLLH LQEKNWSALL TAVVIILTIA GNILVIMAVS LEKKLQNATN YFLMSLAIAD MLLGFLVMPV SMLTILYGYR WPLPSKLCAV WIYLDVLFST ASIMHLCAIS LDRYVAIQNP IHHSRFNSRT KAFLKIIAVW TISVGISMPI PVFGLQDDSK VFKEGSCLLA DDNFVLIGSF VSFFIPLTIM VITYFLTIKS LQKEATLCVS DPGTRAKLAS FSFLPQSSLS SEKLFQRSIH REPGSYGRRT MQSISNEQKA CKVLGIVFFL FVVMWCPFFI TNIMAVICKE SCNEDIIGAL LNVFVWIGYL SSAVNPLVYT LFNKTYRSAF SRYIQCQYKE NKKPLQLILV NTIPALAYKS SQLQMGQKKN SKKDAKSTDN DYSMVALGKQ HSEDAPTDNI NTVNEKVSCV. It is sometimes possible for the material contained within the vial of "5-hydroxytryptamine receptor 2A (HTR2A), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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