Cat Heat Shock 70kDa Binding Protein 1 ELISA Kit | HSPBP1 elisa kit

Cat Heat Shock 70kDa Binding Protein 1 ELISA Kit

• Gene Names: HSPBP1; FES1
• Reactivity: Cat
• Synonyms: Heat Shock 70kDa Binding Protein 1; Cat Heat Shock 70kDa Binding Protein 1 ELISA Kit; HSPBP1 elisa kit

• Reactivity: Cat
• Sequence Length: 362

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 12803139
• NCBI GeneID: 23640
• UniProt Accession #: Q9NZL4; O95351; Q6ZNU5; B3KQP0; B4DG11
• Molecular Weight: 39,474 Da
• NCBI Official Full Name: HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
• NCBI Official Synonym Full Names: HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
• NCBI Official Symbol: HSPBP1
• NCBI Official Synonym Symbols: FES1
• NCBI Protein Information: hsp70-binding protein 1; hsp70 interacting protein; heat shock protein-binding protein 1
• UniProt Protein Name: Hsp70-binding protein 1
• Protein Family: Hsp70-binding protein
• UniProt Gene Name: HSPBP1
• UniProt Synonym Gene Names: HSPBP; HspBP1; HspBP2
• UniProt Entry Name: HPBP1_HUMAN

Uniprot Description

HSPBP1: Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 19q13.42

Molecular Function: enzyme inhibitor activity; protein binding

Biological Process: protein folding; positive regulation of protein ubiquitination; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of catalytic activity