HPV 16/18/45 Assay Kit | HPV16/18/45 assay kit
recomWell HPV 16/18/45
Reactivity
HPV
Synonyms
HPV 16/18/45; recomWell HPV 16/18/45; HPV 16/18/45/recomWell; HPV16/18/45 assay kit
Reactivity
HPV
Related Product Information for HPV16/18/45 assay kit
Qualitative Enzyme immunoassay for detection of E7 oncoproteins from Human Papillomavirus (HPV) types 16, 18, and 45 in cervical smears.
Human Papillomaviruses (HPV) are sexually transmitted viruses frequently occurring all over the world. Almost everyone comes into contact with at least one HP virus during the course of his/her life. In most cases, the infection heals on its own. In rare cases, chronic persistent infections can cause health problems. So far, more than 200 virus types are known of which approximately 40 affect the genitals. Some of these viruses are responsible for the formation of benign genital warts while other types, the so-called high risk types, contribute significantly to the development of cervical, anal, and penile carcinoma and cancer in the area of mouth and throat. The high risk HPV types 16 and 18 are found in 70% of cervical cancer. However, type 45 is also highly associated with risk, particularly for adenocarcinoma, a very aggressive type of cervical cancer.
HPV E7 oncoprotein shares functional similarities (tumor initiation and induction of genomic instability) with such proteins as adenovirus E1A and SV40 large tumor antigen.
HPV E7 plays a central role in both the viral life cycle and carcinogenic transformation.
HPV E7 disrupts the association between cellular differentiation and proliferation in normal epithelium, allowing for viral replication in cells that would no longer be in the dividing population.
recomWell HPV 16/18/45: Secure and simple ELISA format
clear and qualitative results based on the measurement of absorbances.
break-aparts: processing of up to 96 individual samples per run possible.
Human Papillomaviruses (HPV) are sexually transmitted viruses frequently occurring all over the world. Almost everyone comes into contact with at least one HP virus during the course of his/her life. In most cases, the infection heals on its own. In rare cases, chronic persistent infections can cause health problems. So far, more than 200 virus types are known of which approximately 40 affect the genitals. Some of these viruses are responsible for the formation of benign genital warts while other types, the so-called high risk types, contribute significantly to the development of cervical, anal, and penile carcinoma and cancer in the area of mouth and throat. The high risk HPV types 16 and 18 are found in 70% of cervical cancer. However, type 45 is also highly associated with risk, particularly for adenocarcinoma, a very aggressive type of cervical cancer.
HPV E7 oncoprotein shares functional similarities (tumor initiation and induction of genomic instability) with such proteins as adenovirus E1A and SV40 large tumor antigen.
HPV E7 plays a central role in both the viral life cycle and carcinogenic transformation.
HPV E7 disrupts the association between cellular differentiation and proliferation in normal epithelium, allowing for viral replication in cells that would no longer be in the dividing population.
recomWell HPV 16/18/45: Secure and simple ELISA format
clear and qualitative results based on the measurement of absorbances.
break-aparts: processing of up to 96 individual samples per run possible.
Product Categories/Family for HPV16/18/45 assay kit
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Product Notes
The HPV HPV16/18/45 (Catalog #AAA191652) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA191652 Assay Kit recognizes HPV HPV16/18/45. It is sometimes possible for the material contained within the vial of "HPV 16/18/45, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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