Serine/threonine-protein kinase hippo (hpo) Recombinant Protein | hpo recombinant protein
Recombinant Drosophila melanogaster Serine/threonine-protein kinase hippo (hpo), partial
Gene Names
hpo; CG11228; DmelCG11228; dMST; hipo; Hippo; Hpo; MST; MST2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Serine/threonine-protein kinase hippo (hpo); Recombinant Drosophila melanogaster Serine/threonine-protein kinase hippo (hpo); partial; hpo recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-300aa; Partial
Sequence
MSEPEVTSVVDMKSPNISSSCSFFKLKKLSEESLLQPPEKVFDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVESDLHEIIKEISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFI+RNAKHRS
Species
Drosophila melanogaster (Fruit fly)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
75,110 Da
NCBI Official Full Name
hippo, isoform B
NCBI Official Synonym Full Names
hippo
NCBI Official Symbol
hpo
NCBI Official Synonym Symbols
CG11228; DmelCG11228; dMST; hipo; Hippo; Hpo; MST; MST2
NCBI Protein Information
CG11228 gene product from transcript CG11228-RB
UniProt Protein Name
Serine/threonine-protein kinase hippo
Protein Family
UniProt Gene Name
hpo
Uniprot Description
Plays a key role in the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. The Hippo/SWH signaling pathway inhibits the activity of the transcriptional complex formed by Scalloped (sd) and Yki and the target genes of this pathway include cyclin-E (cycE), diap1 and bantam. Phosphorylates Sav, Wts and Th/DIAP1. Regulates the level of Th/DIAP1 apoptosis inhibitor.
Research Articles on hpo
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Product Notes
The hpo hpo (Catalog #AAA1431079) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-300aa; Partial. The amino acid sequence is listed below: MSEPEVTSVV DMKSPNISSS CSFFKLKKLS EESLLQPPEK VFDIMYKLGE GSYGSVYKAV HKESSSIVAI KLVPVESDLH EIIKEISIMQ QCDSPYVVRY YGSYFKQYDL WICMEYCGAG SVSDIMRLRK KTLTEDEIAT ILSDTLQGLV YLHLRRKIHR DIKAANILLN TEGYAKLADF GVAGQLTDTM AKRNTVIGTP FWMAPEVIEE IGYDCVADIW SLGITALEMA EGKPPYGEIH PMRAIFMIPQ KPPPSFREPD RWSTEFIDFV SKCLVKEPDD RATATELLEH EFI+RNAKHR S . It is sometimes possible for the material contained within the vial of "Serine/threonine-protein kinase hippo (hpo), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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