Hydroxyprostaglandin Dehydrogenase 15-(NAD) Recombinant Protein | mHPGD recombinant protein
Recombinant Mouse Hydroxyprostaglandin Dehydrogenase 15-(NAD)
Gene Names
Hpgd; 15-PGDH; AV026552
Purity
Greater than 95.0% as determined by SDS-PAGE
Synonyms
Hydroxyprostaglandin Dehydrogenase 15-(NAD); Recombinant Mouse Hydroxyprostaglandin Dehydrogenase 15-(NAD); 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (EC:1.1.1.141); 15-PGDH; Hpgd; Pgdh1; Prostaglandin dehydrogenase 1; HPGD Mouse; Hydroxyprostaglandin Dehydrogenase 15-(NAD) Mouse Recombinant; mHPGD recombinant protein
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE
Form/Format
Sterile filtered colorless solution
Solution (1mg/ml) contains 20mM Tris-HCl buffer (pH8.0) and 10% glycerol
Solution (1mg/ml) contains 20mM Tris-HCl buffer (pH8.0) and 10% glycerol
Sequence
MGSSHHHHHH SSGLVPRGSH MGS MHVNGKV ALVTGAAQGI GKAFAEALLL HGAKVALVDW NLEAGVKCKA ALDEQFEPQK TLFVQCDVAD QKQLRDTFRK VVDHFGRLDI LVNNAGVNNE KNWEQTLQIN LVSVISGTYL GLDYMSKQNG GEGGIIINMS SLAGLMPVAQ QPVYCASKHG IIGFTRSAAM AANLMKSGVR LNVICPGFVD TPILESIEKE ENMGQYIEYK DQIKAMMKFY GVLHPSTIAN GLINLIEDDA LNGAIMKITA SKGIHFQDYD ISPLLVKAPL TS
Sequence Length
269
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles
Related Product Information for mHPGD recombinant protein
Description: HPGD Mouse Recombinant produced in E Coli is a single polypeptide chain containing 292 amino acids (1-269) and having a molecular mass of 31.6kDa. HPGD is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: HPGD is the essential enzyme of prostaglandin degradation. 15-PGDH protein strongly decreases the biologic activity of these molecules by catalyzing the oxidation of the 15-hydroxyl group of prostaglandins to a keto group. GDH1 is involved in numerous physiologic and cellular processes, for instance inflammation.
Introduction: HPGD is the essential enzyme of prostaglandin degradation. 15-PGDH protein strongly decreases the biologic activity of these molecules by catalyzing the oxidation of the 15-hydroxyl group of prostaglandins to a keto group. GDH1 is involved in numerous physiologic and cellular processes, for instance inflammation.
Product Categories/Family for mHPGD recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
29,181 Da
NCBI Official Full Name
15-hydroxyprostaglandin dehydrogenase
NCBI Official Synonym Full Names
hydroxyprostaglandin dehydrogenase 15 (NAD)
NCBI Official Symbol
Hpgd
NCBI Official Synonym Symbols
15-PGDH; AV026552
NCBI Protein Information
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
UniProt Protein Name
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
UniProt Gene Name
Hpgd
UniProt Synonym Gene Names
Pgdh1; 15-PGDH
Uniprot Description
Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4 ().
Research Articles on mHPGD
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Product Notes
The mHPGD hpgd (Catalog #AAA147094) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGS MHVNGKV ALVTGAAQGI GKAFAEALLL HGAKVALVDW NLEAGVKCKA ALDEQFEPQK TLFVQCDVAD QKQLRDTFRK VVDHFGRLDI LVNNAGVNNE KNWEQTLQIN LVSVISGTYL GLDYMSKQNG GEGGIIINMS SLAGLMPVAQ QPVYCASKHG IIGFTRSAAM AANLMKSGVR LNVICPGFVD TPILESIEKE ENMGQYIEYK DQIKAMMKFY GVLHPSTIAN GLINLIEDDA LNGAIMKITA SKGIHFQDYD ISPLLVKAPL TS. It is sometimes possible for the material contained within the vial of "Hydroxyprostaglandin Dehydrogenase 15-(NAD), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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