Horse Synaptotagmin-11 (SYT11) ELISA Kit | SYT11 elisa kit

Horse Synaptotagmin-11 (SYT11) ELISA Kit

Cat. Num. AAA9904968

• Gene Names: SYT11; SYT12; sytXI
• Reactivity: Horse
• Synonyms: Synaptotagmin-11 (SYT11); Horse Synaptotagmin-11 (SYT11) ELISA Kit; SYT11 elisa kit

• Reactivity: Horse
• Sequence Length: 431

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 216548478
• NCBI GeneID: 23208
• NCBI Accession #: NP_689493.3
• NCBI GenBank Nucleotide #: NM_152280.4
• UniProt Accession #: Q9BT88; Q14998; Q5W0D4; Q68CT5; Q8IXU3; Q96SU2
• Molecular Weight: 48,297 Da
• NCBI Official Full Name: synaptotagmin-11
• NCBI Official Synonym Full Names: synaptotagmin 11
• NCBI Official Symbol: SYT11
• NCBI Official Synonym Symbols: SYT12; sytXI
• NCBI Protein Information: synaptotagmin-11
• UniProt Protein Name: Synaptotagmin-11
• Protein Family: Synaptotagmin
• UniProt Gene Name: SYT11
• UniProt Synonym Gene Names: KIAA0080; SytXI

NCBI Description

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010]

Uniprot Description

SYT11: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Belongs to the synaptotagmin family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q22

Cellular Component: axon; cell junction; dendritic spine; excitatory synapse; integral component of plasma membrane; lysosome; neuron projection; perinuclear region of cytoplasm; phagocytic cup; phagocytic vesicle; plasma membrane; postsynaptic density; presynaptic active zone membrane; recycling endosome; synaptic vesicle; synaptic vesicle membrane; terminal bouton

Molecular Function: beta-tubulin binding; calcium ion binding; calcium-dependent phospholipid binding; clathrin binding; protein binding; protein homodimerization activity; syntaxin binding; translation initiation factor binding; ubiquitin protein ligase binding

Biological Process: calcium ion-dependent exocytosis of neurotransmitter; negative regulation of neurotransmitter secretion; negative regulation of phagocytosis; plasma membrane repair; protein homotetramerization; regulation of calcium ion-dependent exocytosis; vesicle fusion