Human hook homolog 1 (Drosophila) ELISA Kit | HOOK1 elisa kit

Human Protein Hook homolog 1, HOOK1 ELISA Kit

Cat. Num. AAA9322158

• Gene Names: HOOK1; HK1
• Reactivity: Human
• Synonyms: hook homolog 1 (Drosophila); Human Protein Hook homolog 1; HOOK1 ELISA Kit; Human Protein Hook homolog 1 (HOOK1) ELISA kit; HK1; MGC10642; hook homolog 1; HOOK1 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Body fluids, tissue homogenates, secretions or feces samples
• Assay Type: Quantitative Sandwich
• Detection Range: 3.12ng/ml-100ng/ml
• Sensitivity: 1.0ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for HOOK1 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of HOOK1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 7705415
• NCBI GeneID: 51361
• NCBI Accession #: NP_056972.1
• NCBI GenBank Nucleotide #: NM_015888.4
• UniProt Accession #: Q9UJC3; O60561; Q5TG44; A8K8E9
• Molecular Weight: 84,648 Da
• NCBI Official Full Name: protein Hook homolog 1
• NCBI Official Synonym Full Names: hook microtubule-tethering protein 1
• NCBI Official Symbol: HOOK1
• NCBI Official Synonym Symbols: HK1
• NCBI Protein Information: protein Hook homolog 1; hHK1; h-hook1; hook homolog 1
• UniProt Protein Name: Protein Hook homolog 1
• Protein Family: Protein Hook
• UniProt Gene Name: HOOK1
• UniProt Synonym Gene Names: h-hook1; hHK1
• UniProt Entry Name: HOOK1_HUMAN

NCBI Description

This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

HOOK1: Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton. Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Belongs to the hook family.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 1p32.1

Cellular Component: microtubule

Molecular Function: identical protein binding; protein binding; actin binding

Biological Process: protein transport; endosome organization and biogenesis; lysosome organization and biogenesis; early endosome to late endosome transport; multicellular organismal development; endosome to lysosome transport; spermatid development