Rat homer homolog 3 (Drosophila) ELISA Kit | HOMER3 elisa kit
Rat Homer protein homolog 3, HOMER3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
may interact with group I metabotropic glutamate receptors and regulate their coupling to membrane ion channels [RGD, Feb 2006]
Uniprot Description
HOMER3: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses. Belongs to the Homer family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Cellular Component: postsynaptic membrane; cytoplasm; postsynaptic density; plasma membrane; cell junction; cytosol
Molecular Function: protein C-terminus binding; protein domain specific binding; metabotropic glutatmate receptor binding
Biological Process: metabotropic glutamate receptor signaling pathway
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Product Notes
The Rat HOMER3 homer3 (Catalog #AAA9337122) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337122 ELISA Kit recognizes Rat HOMER3. It is sometimes possible for the material contained within the vial of "homer homolog 3 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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