Mouse high mobility group nucleosomal binding domain 3 ELISA Kit | HMGN3 elisa kit

Mouse High mobility group nucleosome-binding domain-containing protein 3, HMGN3 ELISA Kit

Cat. Num. AAA9337448

• Gene Names: Hmgn3; TRIP7; BB071015; 1110002A15Rik; 6330514M13Rik
• Reactivity: Mouse
• Synonyms: high mobility group nucleosomal binding domain 3; Mouse High mobility group nucleosome-binding domain-containing protein 3; HMGN3 ELISA Kit; Mouse High mobility group nucleosome-binding domain-containing protein 3 (HMGN3) ELISA kit; DKFZp686E20226; PNAS-24; PNAS-25; TRIP7; high-mobility group protein HMGN3; thyroid hormone receptor interacting protein 7; thyroid hormone receptor interactor 7; HMGN3 elisa kit

• Reactivity: Mouse

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 21313298
• NCBI GeneID: 94353
• NCBI Accession #: NP_080398.1
• NCBI GenBank Nucleotide #: NM_026122.4
• UniProt Accession #: Q9DCB1; Q7M737; Q99JU1
• Molecular Weight: 10,769 Da
• NCBI Official Full Name: high mobility group nucleosome-binding domain-containing protein 3 isoform Hmgn3a
• NCBI Official Synonym Full Names: high mobility group nucleosomal binding domain 3
• NCBI Official Symbol: Hmgn3
• NCBI Official Synonym Symbols: TRIP7; BB071015; 1110002A15Rik; 6330514M13Rik
• NCBI Protein Information: high mobility group nucleosome-binding domain-containing protein 3
• UniProt Protein Name: High mobility group nucleosome-binding domain-containing protein 3
• Protein Family: High mobility group nucleosome-binding domain-containing protein
• UniProt Gene Name: Hmgn3
• UniProt Entry Name: HMGN3_MOUSE

Uniprot Description

HMGN3: Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function. Belongs to the HMGN family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator

Cellular Component: chromatin; nucleus

Molecular Function: nucleosomal DNA binding; DNA binding; chromatin binding

Biological Process: regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; chromatin modification