Hydroxymethylglutaryl-CoA lyase (HMGCL) Recombinant Protein | HMGCL recombinant protein
Recombinant Chicken Hydroxymethylglutaryl-CoA lyase (HMGCL)
Gene Names
HMGCL; HL
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Hydroxymethylglutaryl-CoA lyase (HMGCL); Recombinant Chicken Hydroxymethylglutaryl-CoA lyase (HMGCL); HMGCL recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-298, Full length protein
Sequence
AFPQRVKVVEVGPRDGLQNEKSVVPTPVKIRLIDMLSETGLPVIEATSFVSPRWVPQMADHAEVMQGINKLPGVSYPVLTPNLKGFQAAVAAGAKEVSIFGAASELFTKKNINCSIEESLERFSEVMNAARAASIPVRGYVSCVLGCPYEGNISAAKVAEVSKKMYSMGCYEISLGDRIGIGTPGSMKEMLAAVMKEVPVGALAVHCHDTYGQALANILVALQMGVSVVDASVAGLGGCPYAQGASGNVATEDLVYMLNGLGIHTGVDLQKLMDTGTFICNALNRRTNSKVSQAACRL
Sequence Length
298
Species
Chicken
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for HMGCL recombinant protein
This protein belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
31,436 Da
NCBI Official Full Name
Hydroxymethylglutaryl-CoA lyase, mitochondrial
NCBI Official Synonym Full Names
3-hydroxymethyl-3-methylglutaryl-CoA lyase
NCBI Official Symbol
HMGCL
NCBI Official Synonym Symbols
HL
NCBI Protein Information
hydroxymethylglutaryl-CoA lyase, mitochondrial
UniProt Protein Name
Hydroxymethylglutaryl-CoA lyase, mitochondrial
UniProt Gene Name
HMGCL
UniProt Synonym Gene Names
HL; HMG-CoA lyase
Uniprot Description
Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism ().
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Product Notes
The HMGCL hmgcl (Catalog #AAA965532) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-298, Full length protein. The amino acid sequence is listed below: AFPQRVKVVE VGPRDGLQNE KSVVPTPVKI RLIDMLSETG LPVIEATSFV SPRWVPQMAD HAEVMQGINK LPGVSYPVLT PNLKGFQAAV AAGAKEVSIF GAASELFTKK NINCSIEESL ERFSEVMNAA RAASIPVRGY VSCVLGCPYE GNISAAKVAE VSKKMYSMGC YEISLGDRIG IGTPGSMKEM LAAVMKEVPV GALAVHCHDT YGQALANILV ALQMGVSVVD ASVAGLGGCP YAQGASGNVA TEDLVYMLNG LGIHTGVDLQ KLMDTGTFIC NALNRRTNSK VSQAACRL. It is sometimes possible for the material contained within the vial of "Hydroxymethylglutaryl-CoA lyase (HMGCL), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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