Mouse High mobility group protein B2 ELISA Kit | Hmgb2 elisa kit
Mouse High mobility group protein B2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
HMGB2: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Belongs to the HMGB family.
Protein type: DNA-binding; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 8 B2|8 29.9 cM
Cellular Component: cell; condensed chromosome; cytoplasm; extracellular space; nuclear chromatin; nucleolus; nucleus; perinuclear region of cytoplasm; protein complex
Molecular Function: chemoattractant activity; damaged DNA binding; DNA bending activity; DNA binding; double-stranded DNA binding; protein domain specific binding; RAGE receptor binding; RNA binding; transcription factor activity; transcription factor binding
Biological Process: defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; inflammatory response to antigenic stimulus; male gonad development; negative regulation of transcription, DNA-dependent; positive regulation of DNA binding; positive regulation of endothelial cell proliferation; positive regulation of erythrocyte differentiation; positive regulation of innate immune response; positive regulation of interferon-beta production; positive regulation of megakaryocyte differentiation; positive regulation of nuclease activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of neurogenesis; regulation of transcription from RNA polymerase II promoter; response to lipopolysaccharide; response to steroid hormone stimulus; spermatid nuclear differentiation; spermatogenesis
Research Articles on Hmgb2
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Product Notes
The Mouse Hmgb2 hmgb2 (Catalog #AAA9427292) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9427292 ELISA Kit recognizes Mouse Hmgb2. It is sometimes possible for the material contained within the vial of "High mobility group protein B2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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