Aryl-Hydrocarbon Receptor Nuclear Translocator 3 ELISA Kit | HIF-3beta/ARNTL elisa kit
Cat Aryl-Hydrocarbon Receptor Nuclear Translocator 3 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Function: Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia
By similarity.
Subunit structure: Heterodimer with HIF1A
By similarity. Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with AHR, AHRR, HIF1A and EPAS1/HIF2A as well as with other bHLH proteins. Interacts with NOCA7 and TACC3
By similarity.
Subcellular location: Nucleus.
Tissue specificity: Was expressed at almost the same level in all tissues except for the heart, liver, and small intestine.
Sequence similarities: Contains 1 bHLH (basic helix-loop-helix) domain.Contains 1 PAC (PAS-associated C-terminal) domain.Contains 2 PAS (PER-ARNT-SIM) domains.
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Product Notes
The Cat HIF-3beta/ARNTL arnt (Catalog #AAA094045) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA094045 ELISA Kit recognizes Cat HIF-3beta/ARNTL. It is sometimes possible for the material contained within the vial of "Aryl-Hydrocarbon Receptor Nuclear Translocator 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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